Agricultura y alimentación
Adaptive respiratory bypass restores oxidative metabolism in NADH dehydrogenase-deficient Escherichia coli
01/10/2026 -
Nicotinamide adenine dinucleotide is central to the cellular redox network and continuously cycles between its oxidized (NAD⁺) and reduced (NADH) forms. Membrane-bound NADH dehydrogenases are the...
Predicting viral host range for reverse zoonosis surveillance
01/10/2026 -
Zoonotic transmission of viruses has triggered major outbreaks throughout history. However, human-to-animal transmission, or reverse zoonotic transmission, also represents an underappreciated public...
Piezophilic activity dominates the Puerto Rico Trench deep subseafloor biosphere
01/10/2026 -
Hydrostatic pressure is a defining feature of the deep ocean, yet how it structures microbial activity across the subseafloor biosphere is poorly understood. Here, we assess pressure effects on...
RecBCD Prevents Bacterial Autoimmunity by Clearing Self-DNA Ends Produced During Replication Termination
01/10/2026 -
Viral-induced DNA damage triggers both eukaryotic and prokaryotic innate immunity. Here, we report that self-DNA ends generated routinely during normal termination of bacterial replication suffice to...
Evolutionary contingency facilitates scent divergence in an emergent orchid population
01/10/2026 -
Reproductive isolation can evolve rapidly even among populations with extensive genetic similarity, but the mechanisms underlying this divergence remain an open question in evolutionary biology....
The best popular-science books of October 2026
01/10/2026 -
With a new book from the late primatologist Frans de Waal and a deep dive into artificial intelligence from New York Times tech columnist Kevin Roose, there is some hard-hitting popular science to...
Alzheimer’s risk gene APOE4 may have a reversible weakness
01/10/2026 -
The Alzheimer’s risk gene APOE4 may actively damage brain blood vessels and sabotage the cellular systems that remove harmful proteins. Researchers were able to reverse some of these effects in...
Could quitting ultra-processed food boost your mental health?
01/10/2026 -
People with depression who dramatically cut ultra-processed foods experienced notable improvements in their symptoms in a small preliminary study. Researchers suspect healthier eating may benefit the...
CycloCross: Adversarial single-cell RNA-seq data translation across species
30/09/2026 -
Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of cellular heterogeneity, yet most datasets are limited to a handful of model organisms, leaving critical gaps in...
Sex-specific differences in ADAR editing patterns in response to SARS-CoV-2 infections
30/09/2026 -
Sex-specific differences in COVID-19 outcomes are well documented, with male sex being a key risk factor for severe disease. Multiple factors, including differences in the expression of Interferons...
Niche differentiation confers coexistence prior to the species boundary in an aquatic plant
30/09/2026 -
Despite the prevailing view that ecological divergence drives speciation, we know little about when or how nascent lineages evolve the ecological differences needed to coexist upon secondary contact....
CHACAM: a cell-cell interaction-guided hierarchical attention model for high-precision cell identity annotation of scRNA-seq data in early C. elegans embryogenesis
30/09/2026 -
Accurate cell identity annotation is essential for reconstructing cell lineages and gene-regulatory networks in embryogenesis. However, in Caenorhabditis elegans (C. elegans) single-cell...
Antibody-recruiting molecules based on mimotope fusion peptides and a dimeric antibiotic
30/09/2026 -
New therapeutic approaches are needed to treat infections due to multidrug resistant (MDR) Gram-negative bacteria. The use of antibody-recruiting molecules (ARMs) is a promising approach to address...
Chocolate Processed by Extrusion Cooking Affects Glucose and Lipid Metabolism in Humans: A Randomized, Double‐Blind, Crossover Trial
30/09/2026 -
The benefits of extrusion‐processed chocolate helped establish a correlation between food processing and glucose and lipid metabolism, enabling the development of palatable and healthy foods to...
Conjugation of Coffee Phenolics With Milk Bioactive Peptides: Characterization of Coffee and Apple Phenolics and Evaluation of Polyphenol Oxidase as a Natural Biocatalyst
30/09/2026 -
Green coffee beans provided a chlorogenic acid (CQA)‐rich extract, while apple juice served as a natural source of polyphenol oxidase (PPO). The coffee phenolics were characterized by HPLC–MS and...
Effects of Supplementing the Diets of Mice With Different Concentrations of Conjugated Linoleic Acid on the Anti‐Inflammatory Function of the Mammary Gland
01/10/2026 -
Dietary conjugated linoleic acid (CLA), a functional fatty acid, exhibits antioxidant and anti‐inflammatory activities. This study assessed its protective effects against mammary gland inflammation...
Pediococcus acidilactici PA53 Supplementation Improves Stool Form and Modulates Gut Microbiota and Inflammatory Responses in Adults With Functional Constipation: A Randomized, Double‐Blind, Placebo‐Controlled Trial
01/10/2026 -
In this randomized, double‐blind, placebo‐controlled trial, 8‐week supplementation with Pediococcus acidilactici PA53 significantly improved stool form in adults with functional constipation....
Comparative Evaluation of White Quinoa and Tri‐Color Quinoa on Indomethacin‐Induced Gastrointestinal Damage
30/09/2026 -
This graphical abstract presents a comparative study on the gastroprotective efficacy of white versus tri‐color quinoa in male rats against indomethacin‐induced gastric injury. Following a...
Gastrodia elata Polysaccharide Attenuates Aging by Modulating Oxidative Stress, Inflammation, and Gut Microbiota
30/09/2026 -
Gastrodia elata polysaccharide (GEP) alleviates aging in mice by activating the Nrf2/Keap1 antioxidant signaling, inhibiting the TLR4/NF‐κB‐driven neuroinflammation, remodeling gut microbiota,...
Relatedness of Gardnerella prophages and their endolysins
29/09/2026 -
The Gardnerella genus includes a complex sub-taxonomy of bacterial species and subgroups which have been implicated in bacterial vaginosis. We analyzed G. leopoldii, G. swidsinski, G. piotii, and G....
Multiple Shifts from Peptide-Based to Metabolite-Based Venoms in Ants
29/09/2026 -
Venom systems are key evolutionary innovations that have contributed to the ecological success of numerous animal lineages. In ants (Formicidae), venom exhibits an exceptional diversity in both...
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