Ciencias de la vida

Prior Bombyx mori latent virus exposure enhances subsequent BmNPV infection and suppresses antiviral responses in the silkworm, Bombyx mori

15/10/2026 - Bombyx mori latent virus (BmLV) is a persistent RNA virus frequently detected in silkworm-derived cell lines and has been reported to interact with B. mori nucleopolyhedrovirus (BmNPV). However,...

Programmable design of functional RNAs through multimodal generative learning

15/10/2026 - RNA engineering is bottlenecked by the tight coupling among sequence, structure, and function, leaving the field reliant on heuristics or screening. We introduce RNAverse, a multimodal generative...

Antibiotic inhibition uncouples growth from horizontal gene transfer

15/10/2026 - Conjugative plasmids often encode resistance to multiple antibiotics, allowing a single mobile genetic element to transfer across diverse selective environments. This co-selection is often invoked to...

Cancer cachexia overrides sex-specific traits in Drosophila

15/10/2026 - Cancer cachexia, a metabolic syndrome characterized by pathologic weight loss, dramatically limits therapeutic options and reduces survival. While the mechanisms by which tumors induce wasting of...

Regulation of target gene expression by chromatin-associated protein-coding transcripts in plants

15/10/2026

Astrocyte fatty acid uptake and ketogenesis in the mediobasal hypothalamus coordinate adaptive metabolic responses against high-fat diet exposure in male rodents

14/10/2026 - The mediobasal hypothalamus (MBH) constitutes a central regulator of energy homeostasis; specialized neurons in this region integrate peripheral metabolic signals to coordinate processes like food...

Mitochondrial respiratory complexes, excitation-contraction coupling and mTOR signaling transcriptional programs are dysregulated in cardiometabolic HFpEF

14/10/2026 - Heart failure is a leading cause of death and disability worldwide. Nearly, half of the cases correspond to HF with preserved ejection fraction (HFpEF), which is predicted to become the most...

Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

14/10/2026 - Autophagy is proposed to protect against aging by clearing damaged cellular constituents. In line with this several life-extending interventions in model organisms show some degree of autophagy...

When label-free morphology is sufficient for targeted cellular measurements

13/10/2026 - Label-free morphology captures cellular responses, but its ability to substitute for targeted cellular measurements depends on the intended use. We assess measurement sufficiency using nearly 10...

Genomic Profiling of Estrogen-Related Receptor Identifies Adult Adipocyte-Specific Targets in Drosophila

13/10/2026 - Adipose tissue is a key metabolic organ for carbohydrate and lipid metabolism. Multiple nutrient sensing pathways and metabolic enzymes operate in adipocytes to control energy production and lipid...

Identification of active deubiquitinases in dendritic cells under unstimulated and activated conditions.

13/10/2026 - Ubiquitination is a post-translational modification with well described roles in the regulation of immune cell function, such as dendritic cells (DCs). DCs are crucial initiators and regulators of T...

Your gut bacteria could be changing how many calories you absorb

12/10/2026 - Scientists have developed a model showing that gut bacteria play a surprisingly important role in how many calories we absorb, meaning food labels may not tell the full story. In a controlled study,...

CXCL-CXCR2 signaling drives cancer-endothelium interactions in SCLC metastatic seeding

12/10/2026 - Small cell lung cancer (SCLC) is a highly metastatic malignancy with tropism to the liver, yet the signals that enable organ-specific metastatic colonization remain largely undefined. During...

Short‐term effects of Brassicaceae crop residue on soil nitrification and nodulation in the subsequent field pea

11/10/2026 - Glucosinolates (GLS) in Brassicaceae crops are known to suppress soil nitrification. Despite widespread inclusion of Brassicaceae species in pulse crop rotations, their effects on soil nitrification...

Unraveling phenotypic variation in multiscale behavioral dynamics

11/10/2026 - Behavioral variability reflects differences in internal and external parameters and provides a substrate for natural selection. However, uncovering its structure is challenging because behavior...

Population genomics of the inquiline social parasite Acromyrmex insinuator and its leaf-cutting ant hosts A. echinatior and A. octospinosus reveals cryptic differentiation and reduced efficiency of selection in the parasite

11/10/2026 - Inquiline social parasites usurp colonies of closely related host ants to exploit their social resources. They are almost invariably rare, patchily distributed and difficult to study. Building on...

Structural basis of context-dependent RORγt target gene activation on chromatin

11/10/2026 - RORγt is a key transcriptional regulator that supports protective pathogen clearance but also drives autoimmune disorders. Genetic studies have identified RORγt mutations that selectively protect...

Neanderthals may have used prehistoric glue as an ancient antibiotic

10/10/2026 - Neanderthals may have used a sticky substance made from birch bark to treat wounds thousands of years before antibiotics existed. Researchers recreated ancient birch tar production techniques and...

Scientists discover why a 100-year-old mushroom disease won't go away

11/10/2026 - Scientists have uncovered a surprising secret behind a mushroom disease that has frustrated growers for more than a century: It involves more than 17 species of harmful bacteria, not just one. The...

Approximate local alignment via chained MEM divergence estimation for detecting horizontal gene transfer

08/10/2026 - Local alignment tools struggle at querying against thousands of bacterial genomes, because the reference indexes are memory-intensive and base-level dynamic programming is slow. We present alamem...

SpatialOmicsLab: an integrated research environment for AI co-scientists in spatial transcriptomics

08/10/2026 - Spatial profiling is moving from method development into a central platform for biological discovery and clinical translation, but analyzing such complex data has become the bottleneck of scientific...