Ciencias de la vida

Prior Bombyx mori latent virus exposure enhances subsequent BmNPV infection and suppresses antiviral responses in the silkworm, Bombyx mori

15/10/2026 - Bombyx mori latent virus (BmLV) is a persistent RNA virus frequently detected in silkworm-derived cell lines and has been reported to interact with B. mori nucleopolyhedrovirus (BmNPV). However,...

Programmable design of functional RNAs through multimodal generative learning

15/10/2026 - RNA engineering is bottlenecked by the tight coupling among sequence, structure, and function, leaving the field reliant on heuristics or screening. We introduce RNAverse, a multimodal generative...

An integrated data exploration engine of knowledge, expression and genetic association for human transposable elements

15/10/2026 - Transposable elements (TEs) constitute a substantial fraction of the human genome and contribute to genomic and epigenomic regulation. However, TE-related knowledge remains fragmented across the...

Non-exonic read content reorganises lncRNA co-expression networks in renal and other cancers

15/10/2026 - Co-expression networks are used to find prognostic lncRNA programmes, but lncRNA quantification depends on unprocessed RNA in the library. In renal cancer (1,062 patients), the leading lncRNA axis...

A quarter of male soldiers in the US could have low testosterone

15/10/2026 - Newly introduced testosterone screening in the US Army could find more than 100,000 male soldiers with low testosterone

Limits of marker information transfer]{Limits of marker information transfer in cross-panel cytometry imputation

14/10/2026 - Marker imputation can bridge cytometry datasets acquired with different panels and platforms. Its validity depends on whether common markers retain information about unmeasured target markers and...

Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

14/10/2026 - Autophagy is proposed to protect against aging by clearing damaged cellular constituents. In line with this several life-extending interventions in model organisms show some degree of autophagy...

A Reproducible Cortical Model of Focal Epileptiform Activity with a Multi-Biomarker Analysis Pipeline

13/10/2026 - The development of surface-based therapeutic strategies, including extracranial illumination and epicortical electrical or optoelectronic neuromodulation, requires experimental models in which focal...

Chromatin Acetylation Overrides Substrate Stiffness-Dependent Mechanoresponse and Lineage Specification in Human Mesenchymal Stem Cells

13/10/2026 - Human mesenchymal stem cells (hMSCs) exhibit a stiffness dependent cellular phenotype and lineage bias. Cells on soft substrate display reduced cell spreading, less cellular traction, smaller and...

Genomic Profiling of Estrogen-Related Receptor Identifies Adult Adipocyte-Specific Targets in Drosophila

13/10/2026 - Adipose tissue is a key metabolic organ for carbohydrate and lipid metabolism. Multiple nutrient sensing pathways and metabolic enzymes operate in adipocytes to control energy production and lipid...

ASC specks and α-synuclein amplify microglial NLRP3 inflammasome activation and co-localize with Lewy body pathology

13/10/2026 - Neuroinflammation is a hallmark of several chronic neurodegenerative disorders, including Parkinson's disease (PD) and other synucleinopathies, and is closely associated with microglial activation....

Increases in therapist-patient physiological synchrony after dog-patient contact in canine-assisted psychotherapy: an exploratory pilot study

13/10/2026 - Introduction: Canine-assisted psychotherapy (CAP) introduces a therapy dog into the therapist-patient relationship and may influence interpersonal processes underlying therapeutic change. This...

Identification of active deubiquitinases in dendritic cells under unstimulated and activated conditions.

13/10/2026 - Ubiquitination is a post-translational modification with well described roles in the regulation of immune cell function, such as dendritic cells (DCs). DCs are crucial initiators and regulators of T...

Your gut bacteria could be changing how many calories you absorb

12/10/2026 - Scientists have developed a model showing that gut bacteria play a surprisingly important role in how many calories we absorb, meaning food labels may not tell the full story. In a controlled study,...

PhageHost-GNN: novelty-aware and locally adaptable strain-level Klebsiella-phage prediction

11/10/2026 - Interest in bacteriophages as alternative treatments for bacterial infections has grown amid the ongoing crisis of multidrug resistance. However, their narrow host range makes it labor-intensive to...

Unraveling phenotypic variation in multiscale behavioral dynamics

11/10/2026 - Behavioral variability reflects differences in internal and external parameters and provides a substrate for natural selection. However, uncovering its structure is challenging because behavior...

Population genomics of the inquiline social parasite Acromyrmex insinuator and its leaf-cutting ant hosts A. echinatior and A. octospinosus reveals cryptic differentiation and reduced efficiency of selection in the parasite

11/10/2026 - Inquiline social parasites usurp colonies of closely related host ants to exploit their social resources. They are almost invariably rare, patchily distributed and difficult to study. Building on...

Sequence context decodes multi-state conformational heterogeneity from crystallographic B-factors

11/10/2026 - Protein function is governed by conformational ensembles, yet the overwhelming majority of experimentally determined structures capture only static snapshots, leaving the multi-state heterogeneity...

Neanderthals may have used prehistoric glue as an ancient antibiotic

10/10/2026 - Neanderthals may have used a sticky substance made from birch bark to treat wounds thousands of years before antibiotics existed. Researchers recreated ancient birch tar production techniques and...

Scientists discover why a 100-year-old mushroom disease won't go away

11/10/2026 - Scientists have uncovered a surprising secret behind a mushroom disease that has frustrated growers for more than a century: It involves more than 17 species of harmful bacteria, not just one. The...

Scientists discover vanilla’s hidden healing potential

12/10/2026 - Scientists have discovered that vanillin, the compound that gives vanilla its distinctive flavor, has powerful properties that could help fight infections, reduce inflammation, and promote wound...