Ciencias de la vida
NUCLEOBASE EDITORS AND USES THEREOF
28/08/2025 -
Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the...
ANTI-CANCER AGENTS
28/08/2025 -
This invention relates to agents, uses and methods for cancer designed to promote anti-tumor effects over a range of different cancers. Exemplary synergistic therapies include compositions of...
CHIMAERIC PROTEINS AND THERAPEUTIC AGENTS
28/08/2025 -
Provided is a chimaeric protein comprising a ubiquitin ligase domain and a RAS-specific endogenous targeting portion. The ubiquitin ligase domain may be a VHL E3 ligase domain, or a fragment or...
Compound - diagnostic marker for kidney cancer, method for detecting enzymatic activity, method for diagnosis of kidney cancer, kit comprising the compound, uses of the compound and method for the treatment of kidney cancer
28/08/2025 -
The invention relates to a novel chemical compound—a diagnostic marker—for use in medicine, more specifically in cancer diagnosis, in particular the diagnosis of kidney cancer. The invention...
VIRAL DELIVERY OF NEOANTIGENS
28/08/2025 -
Disclosed herein are chimpanzee adenoviral vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods...
ENGINEERED CRISPR-CAS13F SYSTEM AND USES THEREOF
28/08/2025 -
The disclosure provides novel engineered Cas13f effector proteins that substantially maintain guide sequence-specific cleavage activity and substantially lack guide sequence-independent collateral...
TARGETED AUGMENTATION OF NUCLEAR GENE OUTPUT
28/08/2025 -
Provided herein are methods and compositions for increasing production of a target protein or functional RNA by a cell.
ORGANIC COMPOSITIONS TO TREAT BETA-CATENIN-RELATED DISEASES
28/08/2025 -
The present disclosure relates to RNAi agents useful in methods of treating Beta-Catenin-related diseases such as adenomatous polyposis of the colon, colorectal cancer, basal cell carcinoma,...
POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR
28/08/2025 -
The present disclosure relates to the technical field of medicines, in particular to a polycyclic poly(ADP-ribose) polymerase (PARP) selective inhibitor compound as shown in general formula (I), a...
COMPOSITIONS AND METHODS FOR TREATING TARDBP ASSOCIATED DISEASES
28/08/2025 -
The present invention relates to the field of antisense oligonucleotides used to reduce expression of the transactive response DNA binding protein 43 (TARDBP) gene which encodes the protein TAR...
ENGINEERED CRISPR-CAS13F SYSTEM AND USES THEREOF
28/08/2025 -
The disclosure provides novel engineered Cas13f effector proteins that substantially maintain guide sequence-specific cleavage activity and substantially lack guide sequence-independent collateral...
NUCLEOBASE EDITORS AND USES THEREOF
28/08/2025 -
Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the...
BIOMETRIC SIGNAL DETECTION DEVICE FOR OCCUPANT IN CABIN AND CONTROL METHOD OF SAME DEVICE
28/08/2025 -
The present invention relates to a device for detecting biometric signal of an occupant in a cabin of a vehicle, the device including: an interface part for receiving vehicle information, and...
METHOD FOR MANUFACTURING A SENSING DEVICE FOR HEAVY METAL DETECTION IN A LIQUID AND SUCH A SENSING DEVICE
13/06/2025 -
The present invention refers to a sensing device (100) for heavy metal detection in a liquid, in particular water, comprising a substrate (30), a microfluidic channel (103), an MoS2-based sensor...
ELECTRONIC DEVICE FOR PROVIDING INFORMATION OF LESIONS AND METHOD OF OPERATING THE ELECTRONIC DEVICE
28/08/2025 -
According to one embodiment of the present disclosure, an electronic device for processing an endoscopic image may comprise a memory configured to store instructions and at least one processor...
SYSTEM FOR INTEGRATION INTO A FRUIT PROCESSING FACILITY
28/08/2025 -
The system comprises one or more transportable bioreactors configured with the ability to conduct aerobic fermentation of fruit biomass. This system integrates three functionalities:...
Formation and filling-reconstruction mechanism of ultra-deep strike-slip fault-controlled reservoirs in Aman transition zone, Tarim basin
25/06/2025 -
A well system (1006) is provided that includes an injection wellbore (1014) having a configuration that traverses an injection formation (1002) and has a horizontal configuration. The injection...
OPTIMIZED CULTURE MEDIA FOR CLOSTRIDIA BACTERIA
28/08/2025 -
The present invention relates to media compositions for culturing bacteria. In particular, the present invention relates to media for culture and/or fermentation of Clostridia bacteria.
Cloning, dignity and ethical reasoning
06/06/2024 -
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Integrated Midline Catheter System
22/08/2025 -
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