Actividades asistenciales

Pyrido[4,3-d]pyrimidine compounds
01/04/2025 - The invention relates to compounds of Formula (I)-(VII), or pharmaceutically acceptable salts thereof, to their use in medicine; to compositions containing them; to processes for their...
Combination therapy for treating prostate cancer
01/04/2025 - The present disclosure provides methods of treating prostate cancer patients with an anti-STEAP1 antigen binding protein such as xaluritamig, in combination with lutetium Lu 177 vipivotide...
PRMT5 inhibitors and uses thereof
01/04/2025 - The disclosure provides for compounds and compositions methods for modulating or inhibiting PRMT5.
Brexpiprazole oral film formulation, preparation method thereof, and use thereof
01/04/2025 - A brexpiprazole oral film formulation, a preparation method thereof, and a use thereof are provided. The brexpiprazole oral film includes an active drug and a film-forming material, the active...
Psychoactive medicines and their use for treating psychiatric and neurological conditions and disorders
01/04/2025 - The invention relates to psychoactive medicines including methylone, 2C-B, MBDB, their respective salts, metabolites, isomers, enantiomers, solvates, isotopologues and isotopomers, polymorphs,...
Pharmaceutical composition, package and manufacturing method thereof
01/04/2025 - The present inventive provides a pharmaceutical composition comprising lyophilized glycolytic enzymes having an excellent titer, and a package comprising the above pharmaceutical composition. The...
FLUOROALKYL-OXADIAZOLES AND USES THEREOF
25/06/2025 - Provided herein are compounds identified as inhibitors of HDAC6 activity that can be used to treat various diseases and disorders.
Nucleic acid molecule comprising intracellular signaling domain and NKp30 transmembrane domain, and chimeric antigen receptor comprising the same
01/04/2025 - Provided is an isolated nucleic acid molecule comprising an intracellular signaling domain and a NKp30 transmembrane domain, and a chimeric antigen receptor comprising the same. The isolated...
NIRAPARIB salts
01/04/2025 - Novel salts of niraparib are provided. Also provided are pharmaceutical compositions comprising those salts, as well as methods and uses pertaining to the same.
Crystalline salts of 2-phenyl-2-aminocyclohexan-1-one derivatives
01/04/2025 - The present disclosure relates to various crystalline salts of (R)-2-(4-fluorophenyl)-2-(methylamino)cyclohexan-1-one, which are useful for treating psychiatric disorders, including treating mood...
Inhibitors of TREK (TWIK related K+ channels) channel function
01/04/2025 - Disclosed is a compound of formula (I): wherein all symbols are defined in the description. Also disclosed are pharmaceutical compositions comprising the compounds, methods of making the...
Compositions and methods for genetically modifying CD70
16/04/2025 - Compositions and methods for editing, e.g., altering a DNA sequence, within a CD70 gene are provided. Compositions and methods for reducing or eliminating CD70 protein expression in a cell are...
AN AUTOMATED TORQUE DEVICE FOR INSTALLING AND EXTRACTING FASTENING ELEMENTS FOR MILL LINERS
06/12/2024 - The invention relates to a torque tool or device for installing and extracting fastening elements for mill liners, such as nuts and washers, the tool being automated with high torque capacity and...
Tomato plant, manufacturing method thereof, DNA fragment, manufacturing method of F1 seed, product comprising tomato plant and manufacturing method thereof
16/04/2025 - The purpose of the present invention is to provide a tomato plant having resistance against root-knot nematodes and leaf mould. An embodiment of the present invention is related to a tomato plant...
Composition for brightening containing sodium pyruvate
16/04/2025 - The present invention relates to a use of a composition in whitening, the composition comprising sodium pyruvate and at least one selected from the group consisting of urea and hydroxyethyl urea....