Salud y calidad de vida

Toward Generalizable Cognitive Impairment Detection with Speech-Based Multimodal Large Language Models

- Cognitive impairment (CI) is a growing public health concern. Early and accurate diagnosis is critical for enabling timely intervention and improving patient outcomes. Speech-based CI detection has...

Climate-resilient electric vehicle charging infrastructure for sustainable cities: An interpretable causal-ensemble framework for preventive maintenance and low-carbon mobility

- Reliable electric vehicle (EV) charging infrastructure is a cornerstone of sustainable, low-carbon cities, yet urban climate stress such as extreme heat, heavy precipitation, and humidity...

RadioTrace: Transmitter-Aware Diffusion for Radio Map Estimation without Deployment-Time Fine-Tuning

- Radio map (RM) estimation aims to reconstruct the spatial distribution of wireless signal characteristics, such as received signal strength (RSS), from sparse measurements, a task that is critical...

A Needs Assessment for Measuring Geographic - Legislative Associations in the U.S. House of Representatives

- Political legislation affects the well-being and livelihoods of constituents. In the U.S. Congress a representative's voting record on bills and legislation is public. These bills have themes...

A Diffusion-Model Subpopulation Digital Twin for Mobile Health Deployment: A Case Study on the HeartSteps Intervention

- Mobile-health interventions increasingly use online learning and decision making algorithms to personalize when to nudge users toward healthier behavior, but a poorly designed algorithm can burden...

A Logic-based Temporal Cohort Discovery Engine: Algorithms, Indices, and Experimental Results on the National Sleep Research Resource

- Large sleep-study repositories contain rich time-stamped physiological annotations, but cohort discovery is still commonly implemented as ad hoc scripts or scalar-index filters. We present a...

Toward Federated Cognitive Digital Twins over the Edge-to-Cloud Continuum

- Digital Twins (DTs) are increasingly adopted to monitor, analyze, and optimize Cyber-Physical Systems (CPSs) through continuous interaction between physical assets and their digital counterparts....

Quality-Aware Multimodal Fusion Reveals Implicit Identity in Valence-Arousal Features

- Conventional face recognition relies on static appearance cues and degrades in unconstrained settings with expression variation, occlusion, and poor lighting. We hypothesize that audiovisual...

Case study: solving P-99 with LPTP and an LLM

- Ninety-Nine Prolog Problems (P-99) is a famous set of Prolog exercises. We solved the first thirty three just by prompting an LLM (Large Language Model). We used Claude from Anthropic. By solved we...

SafeStep: AI-powered Travel Assistance for Elderly People with Frailty or Dementia

- More than a million people in the UK suffer from frailty or dementia, which severely compromise their ability to travel in urban environments. This paper presents SafeStep, an AI-driven travel system...

A stability-preserving polytopal discontinuous Galerkin method for the Fisher-Kolmogorov model with applications to neurodegenerative diseases

- The Fisher-Kolmogorov model is one of the most widely used models in the study of neurodegenerative diseases, owing to its simple structure as a nonlinear reaction-diffusion equation. In particular,...

HiMe: Real-Time Self-Hosted Personal Agent Platform for Health Insights with Wearable Devices

- Traditional approaches to wearable health signal analysis, such as smartwatches, are constrained by rigid analytical frameworks and limited personalisation. The emergence of LLM agents creates a new...

Anti-Goal Reasoning: Rethinking the Theory of Goal Reasoning in Non-Axiomatic Logic

- Goal reasoning in Non-Axiomatic Logic (NAL) explains how an adaptive system derives means for realizing desired events under insufficient knowledge and resources. However, the representation of...

Hierarchical Log-Gaussian Relaxation on a Fixed D3Q125 Velocity Set

- We develop a hierarchical order-resolved relaxation model for a fixed D3Q125 discrete-velocity kinetic formulation. Conventional adaptive collision models often use one scalar rarefaction or...

Evaluating the Effectiveness of Persona Simulation in Opinion Prediction with GPT-4.1

- Persona simulation involves utilizing large language models (LLMs) to anticipate human choices or interactions based on specific characteristic information. To further understand current limitations...

StabilityBench: Benchmarking Instability in LLMs

- AI Assistants are increasingly deployed in high-stakes settings, such as healthcare or government services. Yet their real-world behavior remains poorly understood due to strong context dependence....

Beyond SBDD: Geometric Deep Learning in Polypharmacology and Multi-target Drug Design

- The traditional "one drug, one target" paradigm of structure-based drug design (SBDD) frequently proves inadequate for treating multifactorial diseases such as cancer and neurodegenerative...

A Knowledge-Injection Framework for Zero-Shot Adaptation of LLMs to Delirium Prediction

- Large language models show promise for clinical prediction, but zero-shot performance on specialized tasks is limited by incomplete domain knowledge, especially for smaller locally deployable models....

Distinguishing Artificial from Authentic: Evaluating LLMs for Detecting LLM-Generated Content

- As large language models (LLMs) are increasingly used by students to generate natural language responses and program code, there is growing interest in whether LLMs themselves can be used to...

Trust by Context, Not by Design? A Quantitative Study of Data Donation Willingness for Open-Source Civic AI in Switzerland

- Civic AI systems increasingly support democratic participation, yet interactions with them may reveal sensitive political views, creating tension between improving AI models and residents'...

Microglia extract neuronal proteolytic organelles via skoupocytosis

24/07/2026 - Neurons face unique challenges in maintaining protein homeostasis due to their tortuous morphology and extended processes. Proteolytic organelles are typically transported retrogradely towards their...