Salud y calidad de vida

Comparative Genomics Reveals Genetic Factors Associated with Intraspecific Pigmentation Differences in Cassava

22/09/2026 - Cassava produces starch-filled tubers which are a crucial food source for many people, especially in Africa. This plant species is famous for drought tolerance and resilience, but changing conditions...

Differential Cytotoxicity of PVP-Copper Nanoparticles in Breast Cancer Cell Lines: Insights from Basal Transcriptomic Profiles

22/09/2026 - Breast cancer is a heterogeneous disease comprising molecular subtypes with distinct therapeutic vulnerabilities. Among emerging therapeutic strategies, copper-based nanoparticles have shown...

Endothelium-on-a-chip for permeability studies in diabetic and diabetic kidney disease milieu

22/09/2026 - Organ-on-a-chip (OOC) technology is a valuable tool that can facilitate a faithful replication of target tissues or organs by enabling the application of important physiological cues that cells...

Optimization of a Human Anti-polio Monoclonal Antibody as a Potential Therapeutic Modality

22/09/2026 - Background. Vaccines have been an essential tool in bringing the world close to polio eradication, with over 99.9 percent of the global population free of poliovirus. No antiviral drugs or monoclonal...

Edible batteries power medical devices in the body

21/09/2026

Should we use GLP-1 drugs to treat obesity in children?

22/09/2026 - Children as young as 8 in the US are being prescribed off-label GLP-1 weight-loss drugs, sparking debate about the potential long-term health effects

Amazon study reveals the best strategies for protecting biodiversity and carbon

21/09/2026 - A large Amazon study suggests the most powerful conservation move may be protecting the forests that are already standing. Preventing damage from wildfires and logging delivered the greatest...

Chronic stress may be quietly reshaping your heart

21/09/2026 - Chronic inflammation tied to stress, lifestyle, mental health, and socioeconomic conditions may silently change the heart for years before any symptoms appear. People with the highest inflammation...

Benchmarking confidence estimation and rescoring for cyclic peptide-protein complex predictions

21/09/2026 - Cyclic peptides are a rapidly expanding class of therapeutics, but the reliability of deep-learning structure prediction for cyclic peptide-protein complexes has not been systematically evaluated. We...

Structural changes in autism reflect atypical brain network organization and phenotypical heterogeneity: a deep network approach

21/09/2026 - Autism Spectrum Disorder (ASD) is a developmental disorder characterized by heterogeneity in social and emotional responses, language, and behavior. Assessments such as the Social Responsiveness...

Structural Plasticity and Ligand Promiscuity of CYP3A4 Revealed by Cryo-EM

21/09/2026 - Cytochrome P450 3A4 (CYP3A4) metabolizes roughly half of all marketed drugs, and its inhibition can cause clinically significant drug-drug interactions. The enzyme accommodates chemically diverse...

Large scale prospective evaluation of co-folding across hundreds of Mac1-ligand complexes and three virtual screens

21/09/2026 - Accurate prediction of ligand-bound protein complexes and ranking them by affinity are central problems in drug discovery. While deep learning co-folding methods can help address these challenges,...

Millions take calcium and vitamin D for bone health. A major review finds little benefit

20/09/2026 - A sweeping review of more than 153,000 adults found that calcium and vitamin D supplements, alone or together, do little to prevent fractures or falls in most older people. Researchers say the...

Vulnerability of triple negative breast cancer to daraxonrasib pan-RAS(on) inhibition

18/09/2026 - Triple-Negative Breast Cancer (TNBC) is a clinical subtype where aberrant expression of receptor tyrosine kinases (RTKs) leads to the activation of the RAS-RAF-MEK-ERK pathway contributing to tumor...

Cyclin D-CDK4/6 couple proliferation to membrane and mitochondrial protein supply through a DeSI1 phospho-switch

18/09/2026 - Cyclin D-CDK4/6 complexes drive cell-cycle entry through an RB-E2F-dependent transcriptional program, but how they coordinate proliferation with the membrane and organelle protein supply required for...

Cognitive resilience helps to predict Alzheimer’s dementia

18/09/2026

Ozempic can change your body. Can it change your life?

17/09/2026 - Ozempic and other GLP-1 medications can improve blood sugar, weight, and cardiovascular health, but researchers found little evidence that they also improve mental health, employment, marriage, or...

Spatiotemporal isoform profiling identifies a central activator of microexon splicing in C. elegans

17/09/2026 - Dynamic alternative splicing programs drive tissue specification and organismal development. Here, we present the most comprehensive, tissue-resolved alternative splicing dataset in Caenorhabditis...

Effects of different slow paced breathing regimes on cerebrospinal fluid (CSF) oscillations

17/09/2026 - Cerebrospinal fluid (CSF) transport is crucial for clearing waste from the brain and is largely driven by blood vessel oscillatory dynamics. During non-REM sleep, large oscillations occur in the...

Short bursts of exercise can boost your cognition

17/09/2026 - Just a couple of minutes of walking around or stretching every hour can improve memory and attention span

Scientists find the whole grain “sweet spot” for better heart health

16/09/2026 - Eating four to six servings of whole grains a day may deliver meaningful benefits for heart health, according to a large review of 87 clinical trials. Researchers found improvements in body weight,...