Actividades asistenciales

Conjugados de ligando-fármaco citotóxico y usos farmacéuticos de estos.
05/12/2025 - Proporcionar un fármaco antitumoral que tenga un excelente efecto terapéutico, que sea excelente en cuanto al efecto antitumoral y seguridad. Se proporciona un anticuerpo anti-cadherina 17 que...
Anticuerpos anti-cd33.
12/12/2025 - Se describen anticuerpos aislados que se unen específicamente a una proteína CD33. También se describen ácidos nucleicos, células y usos terapéuticos relacionados.
Anticuerpos que se unen a la proteína de activación de fibroblastos alfa y al receptor de muerte 4
02/02/2026 - La presente invención se refiere a un anticuerpo multiespecífico que comprende al menos una región de unión a FAPα que comprende una primera región variable de cadena pesada y una primera...
Methods of treating brain tumors using combination therapy
30/01/2026 - Provided are methods of treating a brain tumor (glioma) in a patient in need thereof comprising administering to the patient a combination comprising compound (I), Ivosidenib, as shown below and...
METHOD FOR INCREASING CIRCULATING LEVELS OF MESENCHYMAL STEM CELLS VIA ADMINISTRATION TO THE ORO- NASOPHARYNGEAL TRACT
15/01/2026 - Disclosed is a non-invasive method for elevating circulating levels of therapeutically effective mesenchymal stem cells (MSCs). The method comprises (i) selecting, isolating or enriching a...
PHARMACEUTICAL COMPOSITION FOR TREATING TDP-43 PROTEINOPATHY, AND PREPARATION METHOD THEREFOR AND USE THEREOF
29/01/2026 - The present invention belongs to the technical field of pharmaceuticals. Disclosed are a pharmaceutical composition for treating a TDP-43 proteinopathy, and a preparation method therefor and the...
NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA
29/01/2026 - Provided herein are compounds of Formula (I), Formula (II), and Formula (III) or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7 and A are defined herein. Also...
ANTIFUNGAL PLANT PROTEINS, PEPTIDES, AND METHODS OF USE
29/01/2026 - Provided are transgenic plants expressing MtDef5 antifungal proteins and peptides exhibiting high levels of resistance to susceptible fungi. Such transgenic plants contain a recombinant DNA...
PROPHYLACTIC OR THERAPEUTIC AGENT FOR DELIRIUM
15/01/2026 - 본 발명은 멜라토닌 수용체 친화성을 갖는 화합물 (I) 을 함유하는, 섬망의 예방 또는 치료제를 제공한다. 하기 식: JPEGpat00059.jpg3599 (식 중, 각 기호는...
BCMA-TARGETED CAR-T CELL THERAPY FOR MULTIPLE MYELOMA
18/11/2025 - Provided herein are methods of treating a subject who has multiple myeloma and has received one to three prior treatment(s). Infusions of chimeric antigen receptor (CAR)-T cells comprising a CAR...
PROBIOTIC COMPOSITION COMPRISING VIABLE KLEBSIELLA SP. STRAIN ARO112 AS THE ONLY INGREDIENT OR IN COMBINATION WITH SCFA PRODUCING BACTERIA
22/01/2026 - The invention relates to probiotic compositions comprising viable bacteria of Klebsiella strain ARO112, optionally for use as a therapeutic medicament. Compositions of the invention are provided...
INHIBITORY ANTI-CD93 ANTIBODIES
22/01/2026 - The current disclosure relates agents, such as binding proteins, that bind vascular CD93, wherein binding of said agent to CD93 results in of one or more of i) inhibition of perivascular tumor...
NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME
22/01/2026 - The present invention relates to a novel compound for inhibiting nicotinamide phosphoribosyl transferase (NamPT), a composition including the same, and various uses thereof.
N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (1,3-THIAZOLYL)](SUBSTITUTED)CARBOXAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING THE AMIDE COMPOUNDS AND OF THEIR USE
22/01/2026 - The present application discloses specific compounds of Formula (I) and their use in therapy, in particular, their use as Polymerase Theta (Polθ) inhibitors for the treatment of cancer. The...
TREATMENT AGENT FOR LUNG ADENOCARCINOMAS
22/01/2026 - Provided are: a therapeutic agent for NK2 homeobox 1 (NKX2-1)-negative lung adenocarcinoma containing a Porcupine inhibitor as an active component; a NKX2-1-negative lung adenocarcinoma organoid;...
Inhibitors of MENIN-MLL Interaction
22/01/2026 - The present invention is directed to the compounds 101 and 102—inhibitors of the interaction of menin and MLL. The inhibitors described herein can be useful in the treatment of diseases or...
INHIBITORS OF BETA-SECRETASE
10/01/2018 - Present invention relates to spirocyclic acylguanidines and their usage as inhibitors of β-secretase enzyme (BACEl) activity, pharmaceutical compositions containing them, and methods of their...
TREATMENT OF PROTEIN AGGREGATION MYOPATHIC AND NEURODEGENERATIVE DISEASES BY PARENTERAL ADMINISTRATION OF TREHALOSE
15/01/2026 - Disclosed is a method of treatment of a disease associated with abnormal protein aggregation comprising parenterally administering pharmaceutical formulations comprising trehalose. Also disclosed...
COMBINATION THERAPY FOR COPD
11/04/2022 - Aerosol formulations comprising combination of glycopyrronium bromide, formoterol, and beclometasone dipropionate are useful to reduce the frequency of COPD exacerbations. In addition, the drug...