Actividades asistenciales

1-(5-(2-cyanopyridin-4-yl)oxazole-2-carbonyl)-4-methylhexahydropyrrolo[3,4-b]pyrrole-5(1h)-carbonitrile as usp30 inhibitor for use in the treatment of mitochondrial dysfunction, cancer and fibrosis

31/10/2025

BAKING MIXTURE COMPRISING MICROPOWDERED FAT

20/10/2025 - El presente desarrollo describe a una mezcla para hornear a base de grasa micropulverizada para la elaboración de diferentes productos alimenticios. Este producto se propone ofrecer una mezcla...

THERAPY AND PREVENTION OF PRION PROTEIN COMPLEX INFECTIONS IN NON-HUMAN ANIMALS

30/10/2025 - There are disclosed therapies and preventions of prion protein complex infections. The transcription of the amyloid precursor protein gene and PrP gene and the RNA transcript are the rate-limiting...

Wired for growth: neuron-tumour signalling in the lung and brain increases growth of a hard-to-treat cancer

30/10/2025 - The present invention relates to compositions comprising polyinosinic (poly(I))-polycytidylic acid (poly(C)) molecules, or a salt and/or solvate thereof, comprising double-stranded...

Anticuerpo anti-cm bxet, conjugado anticuerpo-fármaco y método de preparación de estos y uso de estos

26/09/2025 - La presente divulgación proporciona un anticuerpo que actúa sobre c-MET o un fragmento de unión al antígeno de este, un conjugado anticuerpo-fármaco y un uso de estos en el tratamiento del...

Dual‐Driven Janus Nanomotors Combined with a Size‐Shrinkage Strategy for Enhanced Tumor Penetration and Synergistic Chemo/Photothermal/Photodynamic Therapy (Adv. Funct. Mater. 43/2025)

25/09/2025 - 본 발명은 불교용의 연등에 관한 것으로, 한지를 사용하여 조명의 은은함은 물론 디자인의 다양성을 제공하면서도 정형화 되어질 수 있는 연등이...

Cell Therapy for Treating Liver Disease

09/10/2025 - The present disclosure provides Hx.001, and methods of using Hx.001 to treat liver disease. In an aspect, Hx.001 can regenerate liver tissue.

BIFUNCTIONAL FUSION PROTEIN COMPRISING ANTI-PD-1 ANTIBODY AND IL-2 MUTANT

23/10/2025 - Provided is a bifunctional fusion protein comprising an anti-PD-1 antibody and an IL-2 mutant. The bifunctional fusion protein comprises the PD-1 antibody and the IL-2 mutant which are connected...

POLYPEPTIDE TARGETING KRAS MUTANT PROTEIN AND USE THEREOF, DRUG, AND METHOD

23/10/2025 - Provided are a polypeptide targeting a KRAS mutant protein and a use thereof, a drug, and a method. The polypeptide can specifically bind to a KRAS G12 mutant protein binding domain, can exhibit...

USE OF GLUCOSE-1-PHOSPHATE IN TREATMENT OF TUMOR

23/10/2025 - Use of glucose-1-phosphate in the treatment of tumors. Specifically, provided are use of glucose-1-phosphate or a pharmaceutically acceptable salt thereof in the preparation of a drug for treating...

USE OF TAFAMIDIS AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF IN PREVENTION, ALLEVIATION, OR TREATMENT OF DISEASES ASSOCIATED WITH HIF-2α

23/10/2025 - Use of tafamidis or a salt thereof in the prevention, alleviation, or treatment of diseases associated with HIF-2α. In vitro experiments prove that tafamidis enhances the transcriptional activity...

CAR-T CELL HAVING GOOD BLOOD-BRAIN BARRIER PERMEABILITY, PRODUCT, AND USE

23/10/2025 - Provided are a CAR-T cell having good blood-brain barrier permeability, a product, and a use. On the basis of the research on CAR-T cell therapy for central nervous system diseases, provided are a...

COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID

23/10/2025 - The present application provides a composition for organ-specific delivery of nucleic acids, which comprises a guided on-target lipid delivery lipid; further, the composition may comprise a helper...

SINGLE FUSION PROTEIN AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

23/10/2025 - The present invention relates to: a fusion protein comprising an IF1 protein and a derived peptide and an Fc region of an immunoglobulin; and a pharmaceutical composition comprising same. The...

ADMINISTRATION AND DOSAGE OF DIAMINOPHENOTHIAZINES

21/10/2025

MODELS FOR PREDICTING MUTANT P53 FITNESS AND THEIR IMPLICATIONS IN CANCER THERAPY

16/10/2025 - The present technology relates to methods, computing devices, and systems for predicting the fitness of mutant p53 based on the loss of transcription factor function and immunogenicity of a...

CAPSID VARIANTS AND METHODS OF USING THE SAME

16/10/2025 - The disclosure is directed in part to variant capsid polypeptides that can be used to deliver payloads.

AAV VECTORS FOR RETINAL AND CNS GENE THERAPY

16/10/2025 - Provided herein are improved rAAV (e.g., rAAV2, rAAVrh8R, etc.) for enhanced gene therapy of ocular disorders or CNS disorders wherein the rAAV comprise one or more substitutions of amino acids...

THERAPEUTIC SYSTEM PROVIDING BALANCED ENERGY TO A USER

16/10/2025 - A therapeutic system including a generator for outputting energy at a first frequency; and at least one probe having a skin contacting surface the probe electrically connected to the generator....

TREATMENT OF INSOMNIA USING AUDITORY FEEDBACK

09/10/2025 - The present invention relates to a method for treatment insomnia using auditory feedback. The treatment method according to the present invention involves identifying the periodicity of the...

SYSTEMS AND METHODS FOR PROVIDING DIGITAL HEALTH SERVICES

09/10/2025 - The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are...