Actividades asistenciales

PEPTIDE-BOUND BORON CLUSTER COMPLEX FOR USE IN BORON NEUTRON CAPTURE THERAPY (BNCT)
19/08/2026 - [0001] The present invention relates to a peptide-bound boron cluster complex for use in boron neutron capture therapy (BNCT). The present invention covers a library of complexes where one or...
ORAL AND SUBLINGUAL FORMULATIONS OF XANTHINE OXIDASE INHIBITORS AND METHODS OF TREATING DISEASE
30/07/2026 - The invention features formulations and compositions for oral and sublingual film administration of pharmaceutical products including xanthine oxidase inhibitors and methods of enhancing...
METHODS AND COMPOSITIONS COMPRISING ONCOLYTIC VIRUSES EXPRESSING GPC3 AND GPC3-TARGETED THERAPIES
13/08/2026 - Described herein, inter alia, are oncolytic viruses expressing a glypican-3 (GPC3) and methods for treating a patient suffering from a solid tumor by administering an oncolytic virus expressing a...
METHOD OF TREATING MESOTHELIOMA
13/08/2026 - Methods for treating mesothelioma by administering the compound TT-4 (6-oxo-l-propyl-8-[l-(3-trifluoromethyl-benzyl)­lH-pyrazol-4-yl]-6, 7-dihydro-lH-purine-2-carbonitrile) to selectively...
COMPOUNDS FOR LYSINE ACETYLTRANSFERASE 6 (KAT6) INHIBITION AND THERAPEUTIC APPLICATIONS THEREOF
13/08/2026 - The present disclosure relates to compounds represented by one of structural formulas (I'), (I), (II), and (III) or a pharmaceutically acceptable salt thereof: Further disclosed are pharmaceutical...
COMPOUNDS CONTAINING FUSED TRICYCLIC RINGS AS PI3K INHIBITORS
13/08/2026 - Novel PI3K inhibitors of the general Formula (1) are described along with methods of their preparation and their use in the treatment of diseases associated with the elevation or activation of the...
NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREIN
06/08/2026 - Provided are compounds of Formula (I): or pharmaceutically acceptable salts thereof, which are useful for the modulation of nicotinic acetylcholine receptors (nAChRs), specifically the α6β4...
COMBINATION OF OBEFAZIMOD AND ITS DERIVATIVES WITH A ALPHA4BETA7 ANTI-INTEGRIN
05/08/2026 - A method of treating a patient with moderate-to-severee traumatic brain injury (TBI) undergoing emergency craniotomy includes administering, in addition to orthodox therapy (OT), intravenous...
SMALL MOLECULE INHIBITORS OF KRAS PROTEINS
30/07/2026 - Compounds of Formula (I) or their pharmaceutically acceptable salts can inhibit the G12C, G12D, G12V, and/or G13D mutants of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as...
COMBINATION THERAPIES FOR USE IN THE TREATMENT OF BREAST CANCER
30/07/2026 - Provided are combination therapies comprising inavolisib, a CDK4/6 inhibitor (e.g., palbociclib, ribociclib or abemaciclib), and letrozole; and methods of treating endocrine-sensitive...
PURINE COMPOUNDS AND THEIR PHARMACEUTICAL USE
30/07/2026 - The current invention relates to a compound of formula (I), a pharmaceutical composition comprising said compound, a combination therapy and use thereof in a medicament or as therapy in a...
MULTI-FUNCTIONAL PROTEIN COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF
30/07/2026 - Provided here are multi-functional compositions containing an elastin-like-polypeptide (ELP) scaffold containing two or more antigen-binding components or biological response modifiers. These...
EPCAM IMMUNOCONJUGATES AND THERAPEUTIC USES THEREOF
30/07/2026 - The disclosure generally relates to methods of treatment using conditionally activatable masked immunoconjugates comprising antibodies and antibody fragments that specifically bind human EpCAM, as...
METHODS FOR TREATING P53-ASSOCIATED CANCER
30/07/2026 - This disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts thereof, that restore p53 function. These compounds are useful, e.g., for treating a disease in which...
ADMINISTRATION OF YUNNAN BAIYAO OR XINGNAOJING IN PATIENTS WITH MODERATE-TO-SEVER TRAUMATIC BRAIN INJURY AND CRANIOTOMY
30/07/2026 - A method of treating a patient with moderate-to-severee traumatic brain injury (TBI) undergoing emergency craniotomy includes administering, in addition to orthodox therapy (OT), intravenous...
AN APPLICATION OF MOXIBUSTION ON THE TIANSHU ACUPOINT IN REVERSING THE DISAPPEARANCE REACTION OF ABDOMINAL MACROPHAGES
08/07/2026 - The invention discloses the application of moxibustion on the Tianshu acupoint in reversing the disappearance reaction of abdominal macrophages, belonging to the field of moxibustion technology....
PHARMACEUTICAL DOSAGE FORMS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC CONDITIONS
09/07/2026 - Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is...
COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OF RNAi
23/07/2026 - The present disclosure provides compositions and methods related to drug responsive domain (DRD)-regulatable RNA interference (RNAi). Such compositions and methods provide for inhibitory RNA...
METHODS FOR SELECTIVELY DEGRADING PROTEINS
09/07/2026 - The present disclosure relates to method for selectively degrading proteins in a cell. the present disclosure further relates to methods for treating a disease or disorder characterized by cyclin...
OXYGEN CONCENTRATOR
09/07/2026 - The present specification relates to the field of ventilation therapy apparatuses. Provided is an oxygen concentrator. The oxygen concentrator comprises a main support, a compressor and an...
POLYMORPHIC COMPOUNDS AND USES THEREOF
23/07/2026 - The present invention provides freebase and salt forms useful for treating various SMARCA2-mediated disorders, such as cancer, by the administration of small molecule therapeutics that act as...