Actividades asistenciales
Aeronáutica y espacio
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Bienes/productos consumo
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Transformación digitalActividades asistenciales
AFUCOSYLATED ANTI-FGFR2IIIB ANTIBODIES
13/12/2024
SGC STIMULATORS
13/12/2024
ARTIFICIAL IMMUNE RECEPTORS
12/12/2024 -
The present disclosure provides novel polypeptides, so called artificial immune receptors or AlRs, that are novel tools for cellular therapies. AIR-expressing regulatory T cells sense these...
TLR9-TARGETED SPHERICAL NUCLEIC ACIDS HAVING POTENT ANTITUMOR ACTIVITY
12/12/2024 -
Aspects of the invention relate to immunostimulatory spherical nucleic acids (IS-SNA) for the treatment of a disorder, such as cancer. The IS-SNA may be administered together with a checkpoint...
FUSION PROTEIN COMPRISING LIGHT PROTEIN AND ANTI-FAP ANTIBODY AND USES THEREOF
12/12/2024 -
A fusion protein comprising a LIGHT protein and an antigen-binding site that specifically binds to FAP may exhibit anticancer effects. In particular, the fusion protein efficiently targets cancer...
COMBINATION THERAPY COMPRISING SIRP ALPHA FUSION PROTEIN AND ANTI-CD19 ANTIBODY FOR TREATMENT OF CANCER
12/12/2024 -
Combination therapies comprising a SIRPaFc fusion protein and an anti-CD19 agent are provided. The combination therapies can optionally further include an E3 ubiquitin ligase modulator.
COMPOSITIONS AND METHODS FOR TREATING MYELIN DISORDERS
12/12/2024 -
A method of enhancing oligodendrocyte progenitor cell (OPC) migration, differentiation, proliferation and/or maturation in a subject in need thereof includes administering to the subject a...
MUSCARINIC RECEPTOR AGONISTS
06/11/2024 -
Esta invención se refiere a compuestos y sales de los mismos que son agonistas de receptores muscarínicos, útiles en el tratamiento de enfermedades mediadas por receptores muscarínicos....
COMBINATION THERAPY FOR THE TREATMENT OF PANCREATIC CANCER
10/12/2024 -
...
Hydrotherapy system
10/12/2024 -
A hydrotherapy system can include a tub of tempered water, a cold water tank, and a refrigeration system. The system cools the water in the tub following initial immersion of the patient by using...
CYCLIC POLYPEPTIDE CARRIER FOR EFFICIENT DELIVERY OF NUCLEIC ACID, AND VARIANTS THEREOF
12/12/2024 -
The present invention relates to a novel cyclic peptide carrier in the field of pharmaceutical technology and its various forms, where the cyclic peptide has the general sequence formula...
HYDROGENATED QUINOXALINES
12/12/2024 -
Provided is a therapeutic agent for ADHD having an efficacy comparable to that of central nervous system stimulants and the same low risk of drug dependence and abuse as existing non-central...
METHODS FOR UPREGULATING SHANK3 EXPRESSION
12/12/2024 -
Aspects of the disclosure relate to non-naturally occurring constructs for the activation of Shank3 gene expression, AAV vectors comprising the constructs, and gene therapy methods.
COMPOSITIONS AND METHODS FOR TARGETED PARTICLE PENETRATION, DISTRIBUTION, AND RESPONSE IN MALIGNANT BRAIN TUMORS
12/12/2024 -
Described herein are nanoparticle conjugates that demonstrate enhanced penetration of tumor tissue (e.g., brain tumor tissue) and diffusion within the tumor interstitium, e.g., for treatment of...
DENERVATION THERAPY
12/12/2024 -
Example systems and techniques for denervation, for example, renal denervation. In some examples, a processor determines one or more tissue characteristics of tissue proximate a target nerve and a...
COMBINATION THERAPY FOR TREATING CANCER
10/12/2024
BCMA-TARGETED CAR-T CELL THERAPY FOR MULTIPLE MYELOMA
10/12/2024 -
Provided herein are methods of treating a subject who has multiple myeloma and has received one to three prior treatment(s). Infusions of chimeric antigen receptor (CAR)-T cells comprising a CAR...
