Telecomunicaciones, información y comunicación
FlexiTAC enables controllable PROTAC linker generation across diverse structural settings using a Bayesian flow network with posterior guidance
30/08/2026 -
Linker chemistry and conformation are central determinants of PROTAC activity, shaping ternary-complex geometry, cooperativity, target-lysine presentation and cellular permeability. Existing linker...
Metabolite co-variation networks reveal keystone functions and an emergent pathogen state in the human urobiome.
30/08/2026 -
Microbial communities are dynamic, adaptive ecosystems whose collective behavior emerges from metabolic interactions such as cross-feeding, competition, and cooperation, rather than taxonomic...
PhageTransformer - scalable and accurate host assignments for bacteriophages
30/08/2026 -
Bacteriophages can only be understood through their interactions with bacterial hosts. As environmental sequencing efforts expanded, the number of available phage genome sequences has exploded, yet...
VGLL4 promotes thoracic aortic aneurysm and dissection by disrupting extracellular matrix homeostasis via WISP1-mediated TIMP3/MMP9 imbalance
30/08/2026 -
Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening disease characterized by progressive medial degeneration, impaired mechanical integrity, and extracellular matrix (ECM)...
Development of a Primary Visual Cortex Model to Investigate Cortical Visual Prosthesis Stimulation
30/08/2026 -
A new electrical stimulation focused computational model of the visual cortex had been created to aid in the development of cortical visual prosthesis. The model consists of 10,666 biophysical...
Substrate Profiling of RNF216 Uncovers a Translation-Linked OTUD4 Regulatory Axis
30/08/2026 -
Mutations in the E3 Ubiquitin (Ub) ligase RNF216 cause Gordon Holmes syndrome (GHS), a neurodegenerative disorder accompanied by neuroendocrine disruption. We developed an orthogonal ubiquitin...
Scientists discover why damaged nerves struggle to heal
28/08/2026 -
Scientists have identified a protein that acts like a brake on the nervous system’s ability to repair damaged connections. Blocking AHR helped injured nerve fibers regrow and improved movement and...
Some signs of quantum gravity may be an illusion
29/08/2026 -
Quantum mechanics and Einstein’s theory of gravity explain almost everything we see in nature, yet physicists still do not know how to unite them. A new theoretical framework suggests that some...
Australia’s red soil may be hiding a massive clean energy source
29/08/2026 -
Researchers have discovered that Western Australia’s iron-rich rocks can naturally generate hydrogen and that the process may be boosted to produce much larger amounts. If it can be scaled up, the...
IBM quantum computer solves classically intractable problem in 15 minutes
30/08/2026 -
IBM and University of Chicago researchers have completed a quantum computation that leading classical methods could not practically reproduce. The system used 70 error-corrected logical qubits and...
Accelerating Materials Discovery: A Review of Machine Learning in X‐Ray Absorption Spectroscopy
30/08/2026 -
This review systematically details how machine learning transforms X‐ray absorption spectroscopy (XAS) analysis. It covers advanced deep learning architectures for structure‐spectra mapping and...
A Multistage Venturi Amplifier for Rapid Inflation of Soft Robots
30/08/2026 -
This work presents the amplifier inflator for soft robotic systems (AIRS), a compact, lightweight, and effective device for rapidly deploying inflatable structures to high pressure. By integrating a...
Cross‐Sectoral AI Integration Is Essential to Tackling Food Waste and Food Insecurity: A Roadmap for Developing Resilient Food Systems
30/08/2026 -
As food insecurity and global food demands surge, artificial intelligence (AI)‐based technologies offer promising opportunities to reduce food loss and waste. In this perspective, current AI...
Individual Differences in Dopaminergic Modulation of Exploration-Exploitation Behaviour
27/08/2026 -
Dopamine (DA) has been implicated in exploration-exploitation behaviour, i.e., exploring novel, potentially better options vs. exploiting known, previously rewarding options. Impairments in this...
Fusion in the periodic Temperley–Lieb algebra: General definition of a bifunctor, by Yacine Ikhlef, Alexi Morin-Duchesne
27/08/2026 -
The periodic Temperley–Lieb category consists of connectivity diagrams drawn on a ring with $N$ and $N'$ nodes on the outer and inner boundary, respectively. We consider families of modules,...
AutoPot: Automated and massively parallelized construction of machine-learning potentials, by Max Hodapp, Guillaume Anciaux
28/08/2026 -
Machine-learning potentials (MLIPs) have been a breakthrough for computational physics in bringing the accuracy of quantum mechanics to atomistic modeling. To achieve near-quantum accuracy, it is...
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