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Path Integration Promotes Flexible Navigational Decision Making
08/10/2026 -
Flexible decision making depends on internal representations that capture the latent structure of a task, allowing prior knowledge to be applied in novel circumstances. Spatial navigation provides a...
Approximate local alignment via chained MEM divergence estimation for detecting horizontal gene transfer
08/10/2026 -
Local alignment tools struggle at querying against thousands of bacterial genomes, because the reference indexes are memory-intensive and base-level dynamic programming is slow. We present alamem...
SpatialOmicsLab: an integrated research environment for AI co-scientists in spatial transcriptomics
08/10/2026 -
Spatial profiling is moving from method development into a central platform for biological discovery and clinical translation, but analyzing such complex data has become the bottleneck of scientific...
drugMR: A multi-omics pipeline for genetically anchored drug-target discovery
08/10/2026 -
Motivation: Genetically supported drug targets are an estimated 2.6 times more likely to succeed clinically, yet a disease association alone does not show which protein to target, in which direction,...
Social feedback structures stay/switch decision-making in Drosophila
08/10/2026 -
Within natural environments, different sensory stimuli can drive mutually-exclusive behaviors such as fighting, feeding, or courting. When experiencing competing cues, how do animals decide to...
Number of known species of giant waterlilies almost doubles
08/10/2026 -
A new species of giant waterlily identified with the help of social media and satellite photos is just one of three discovered in the past few years
AI or ‘super intelligence’? Trump isn’t the only one who is confused
08/10/2026 -
US President Donald Trump has declared that artificial intelligence should now be called “super intelligence”. Columnist Jacob Aron explains where that term came from and explores whether its...
$c=1$ strings as a matrix integral, by Scott Collier, Lorenz Eberhardt, Victor A. Rodriguez
08/10/2026 -
We study the perturbative $S$-matrix of the $c=1$ string and show that it admits a description in terms of a double-scaled (0+0)-dimensional matrix integral based on the spectral curve $\mathsf{x}(z)...
Attention-based foundation model for quantum states, by Timothy Zaklama, Daniele Guerci, Liang Fu
08/10/2026 -
We present an attention-based foundation model architecture for learning and predicting quantum states across Hamiltonian parameters, system sizes, and physical systems. Using only basis...
PRECISE: Reducing the bias of LLM evaluations using prediction‐powered ranking estimation
08/10/2026 -
Evaluating the quality of search systems traditionally requires a significant number of human relevance annotations. In recent times, several systems have explored the usage of Large Language Models...
Toward an enhanced scalability framework for human‐multi‐agent teams
08/10/2026 -
As autonomous systems become increasingly capable, the deployment of Human‐Multi‐Agent Teams (HMATs) offers immense potential for executing complex, decentralized tasks. However, realizing this...
General‐purpose agents in human‐machine teams: Can we preserve meaningful human control?
08/10/2026 -
As General‐Purpose AI (GPAI) grows more capable of cross‐domain reasoning and multi‐agent coordination, it reshapes the design space of military human‐machine teams and introduces new...
C3a receptor signalling in ObRb-expressing neurons promotes leptin resistance and obesity-associated cardiac remodelling
07/10/2026 -
Obesity is associated with hypothalamic inflammation, leptin resistance and increased cardiometabolic risk, but the neuroimmune signals linking nutrient excess to these outcomes remain incompletely...
Structure-based virtual screening reveals new metabolite interactions and modulators of human glucose-6-phosphate isomerase
07/10/2026 -
Exploring the ability of metabolic enzymes to interact with diverse small molecules can provide insights into their ligand recognition and activity regulation. Glucose-6-phosphate isomerase (GPI) is...
A quantitative portrait of habituation in Stentor coeruleus
07/10/2026 -
Habituation—the decrement in response to a series of stimuli—is a widespread form of learning observed across many organisms, including the unicellular organism Stentor coeruleus . A lesser-known...
Stimulating a NTS to LC circuit elicits anxiety-like behavior and state-dependent autonomic output.
07/10/2026 -
Understanding how the brain integrates internal bodily signals to shape behavior is essential for characterizing the neural basis of interoception. Here, we investigate whether the nucleus of the...
