Telecomunicaciones, información y comunicación
Metabolic-epigenetic coupling between leucine catabolism and glycolysis drives CDK4/6 inhibitor resistance
24/09/2026 -
Resistance to CDK4/6 inhibitors limits the durability of therapy for ER+ breast cancer. Despite the identification of mechanisms that regulate resistance, the metabolic adaptations that enable...
Topotecan Syndergizes with SP141 in the Management of Uveal Melanoma
24/09/2026 -
Purpose: Uveal melanoma (UM) is a rare but aggressive intraocular malignancy originating in the uvea (choroid, iris, and ciliary body). Despite primary treatment, 50% of UM patients develop...
Redundant contacts and force redistribution stabilize limbless vertical climbing
24/09/2026 -
Animals navigating complex vertical environments must secure stable footholds, a challenge for species without feet. While arboreal climbing has evolved repeatedly in snakes, the physical mechanisms...
Endogenous oxytocin reconfigures brainwide network dynamics toward salience-related states
24/09/2026 -
Oxytocin (OXT) can exert diverse effects across social, affective and motivational domains, yet its impact on brain function at the systems level remains unclear. Here, we combine chemogenetics with...
Phase Separation Potential of Marsupial RSX RNA Reveals Convergent Evolution of X-Chromosome Inactivation Mechanisms
24/09/2026 -
Background: X-chromosome inactivation (XCI) evolved independently in eutherian and marsupial mammals, where it is orchestrated by the unrelated long non-coding RNAs Xist and RSX, respectively. Xist...
Integrated anthocyanin profiling and transcriptome analysis identify candidate genes associated with petal color variation in Cyclamen persicum
24/09/2026 -
Petal coloration is a key ornamental trait in Cyclamen persicum Mill. and is closely associated with anthocyanin composition and relative accumulation, yet the major anthocyanins and candidate...
When will the AMOC collapse? We don’t know, but should still prepare
23/09/2026 -
Uncertainty about when or even if the Atlantic Meridional Overturning Circulation, a vital ocean current, might collapse has been an excuse to ignore the risk, but that actually makes it even more...
Scientists say a critical Atlantic Ocean current is weakening and the effects could be global
23/09/2026 -
Scientists have found strong observational evidence that a key part of the Atlantic Meridional Overturning Circulation has been weakening across a wide stretch of ocean for nearly two decades. The...
Lorentz-equivariance without limitations, by Luigi Favaro, Gerrit Gerhartz, Fred A. Hamprecht, Peter Lippmann, Sebastian Pitz, Tilman Plehn, Huilin Qu, Jonas Spinner
23/09/2026 -
Lorentz Local Canonicalization (LLoCa) ensures exact Lorentz-equivariance for arbitrary neural networks with minimal computational overhead. For the LHC, it equivariantly predicts local reference...
Interbody Wire for Reconfigurable Robots: Bridging Integrated Morphological Reconfiguration and Distributed Wire‐Mediated Cooperation
23/09/2026 -
TwinX shows how a single interbody wire connecting two robots can support both integrated morphological reconfiguration and distributed wire‐mediated cooperation. When the robots dock, they...
A parallel control architecture combining muscle-specific motor drive with broadly expressed oscillatory inputs shaping motor neuron synchronization
23/09/2026 -
It remains unknown whether oscillatory brain activity associated with sensorimotor behavior is routed selectively to task-relevant muscles or expressed more broadly, including in task-irrelevant...
Dimensional and Categorical Predictors of Theory of Mind Network Activation: A transdiagnostic fMRI Study in Psychiatric Inpatients
23/09/2026 -
Socio-cognitive alterations are widely observed across different psychiatric conditions, yet it remains unclear whether these deficits map onto distinct diagnostic categories or represent a shared...
New perspectives in assessing environmental risks for birds: a simple TKTD framework to link growth and reproduction energy budget to chemical stress
23/09/2026 -
Assessing the risk of pesticides to birds requires models that can extrapolate laboratory data to realistic exposure scenarios. In this work, we propose a new modeling framework BIRDkiss (Bird -...
RepGene: Auditing Condition-Specific Fusion Biases for Multi-View Gene Representations
23/09/2026 -
This study evaluates how multi-view gene representations should be compared under a matched contract. Each of 18,460 genes is described by five aligned views: DNA sequence-derived features (D), RNA...
The end of humanity? What would happen if the Yellowstone supervolcano erupted now
22/09/2026 -
A Yellowstone super-eruption would begin not with a sudden surprise, but with weeks of increasingly alarming warning signs such as migrating earthquake swarms, rapid ground uplift, changing geysers,...
The LHC just ruled out another hiding place for quantum black holes
22/09/2026 -
Physicists searching through Large Hadron Collider data found no evidence that the machine has been producing microscopic quantum black holes, but the result sharply narrows where such exotic physics...
Quantitative approach for the Dicke-Ising chain with an effective self-consistent matter Hamiltonian, by Jonas Leibig, Max Hörmann, Anja Langheld, Andreas Schellenberger, Kai Phillip Schmidt
22/09/2026 -
In the thermodynamic limit, the Dicke-Ising chain is known to map exactly onto an effective self-consistent matter Hamiltonian with the photon field acting solely as a self-consistent effective...
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