Telecomunicaciones, información y comunicación
A versatile and stable reporter platform for human rhinovirus and other enteroviruses
05/10/2026 -
Human rhinovirus (HRV), a major cause of upper respiratory infections, has increasingly been associated with lower respiratory tract disease. Although tools to investigate HRV pathogenesis are...
An Expanded Lpt Pathway Couples Surface Lipoprotein Export to Outer Membrane Vesicle Biogenesis in Bacteroides
05/10/2026 -
The ecological dominance of Bacteroidota in the human gut microbiota derives from their exceptional capacity to metabolize diverse dietary and host-derived glycans. This ability relies on...
Hidden but Expanding Sampling Bias Distorts Prokaryotic Genome Collections
05/10/2026 -
Public genome collections underpin our understanding of bacterial diversity and the distribution of traits such as antibiotic resistance. Their growing size promises an increasingly complete view of...
trFlow: ultrafast all-atom protein conformational ensemble generation via conditional flow matching
05/10/2026 -
Generating diverse, all-atom protein conformations remains challenging, especially for recovering alternative functional states and modeling conformational ensembles. We present trFlow, an ultrafast...
Killer meiotic driver prevents chromosome loss and enhances fitness in a fungal pathogen
05/10/2026 -
Fungal pathogens often carry dispensable chromosomes (DCs) that confer a selective advantage in adverse environments or during host infection but can be spontaneously lost under non-selective...
Can we harness the brain’s deep-cleaning system to prevent Alzheimer’s?
05/10/2026 -
The glymphatic system is the brain's recently discovered network for flushing out toxins. Now, we're uncovering surprising ways to boost it to protect brain health
This mysterious hole on the Moon may open into a giant cave
05/10/2026 -
NASA has selected the GIMLI project to investigate whether the Marius Hill Pit opens into a vast underground cave or lava tube. Using radar, seismic sensors, gravity measurements, and cameras,...
Complex folding kinetics of multi-domain proteins disentangled with periodic forces by magnetic tweezers
04/10/2026 -
Force spectroscopy yields direct access to the interplay between free energy and transition kinetics of proteins and nucleic acids. Yet, complex molecules such as multi-domain proteins exhibit...
Kidzoi Enables Cell-Type-Specific Regulatory Activity and Variant Effect Prediction in Kidney
04/10/2026 -
Sequence-to-function (S2F) deep learning models predict genome-wide functional profiles directly from DNA sequences and have significantly advanced our understanding of gene regulation. However,...
Preoptic transcriptomes during courtship reveal the molecular basis of behavioral coordination in a highly social cichlid
04/10/2026 -
Human and non-human animals often coordinate their behavior, a phenomenon thought to strengthen relationships by enabling sequential assessment of an interaction partners quality as a mate or rival,...
APOE4 reduction in vascular-associated fibroblasts decreases cerebral amyloid angiopathy and associated vascular dysfunction
04/10/2026 -
Cerebral amyloid angiopathy (CAA), characterized by cerebrovascular amyloid deposition, is strongly associated with Alzheimer's disease, ischemic injury, and lobar hemorrhages. APOE4 is the strongest...
Scale-mixture Langevin sampling in the subspaces of recurrent cortical circuit dynamics
04/10/2026 -
Recurrent cortical circuits are hypothesized to perform Bayesian posterior sampling through their stochastic dynamics. Yet identifying which sampling algorithm a circuit intrinsically implements, as...
Integrating cell-state and enhancer constraints discriminates models of PU.1 regulation during hematopoietic differentiation
04/10/2026 -
Distinct PU.1 levels are associated with progenitor, B-cell, and macrophage states during hematopoietic differentiation. A previous dynamical-systems model attributed these levels to multistability...
Game Theory Research on the Development and Promotion of Artificial Intelligence Teaching Platform Based on Multi-Participant University-Enterprise Collaboration
02/10/2026 -
Sage Open, Volume 16, Issue 4, October-December 2026. With the deep integration of artificial intelligence and education, university-enterprise cooperation has become a key approach for the...
Leucine does more than build muscle. It powers up your cells
03/10/2026 -
The essential amino acid leucine can boost cellular energy production by protecting key proteins on mitochondria from being destroyed. The discovery reveals a new connection between nutrition and...
Your gut bacteria may reveal how fast your brain is aging
04/10/2026 -
A UCLA study links faster brain aging to specific gut bacteria and chemical byproducts, with older-looking brains also associated with poorer memory, focus, and mood. The findings suggest that...
“Relief empire”: Racial aphasia, colonial unknowing and international organizations in the global governance of refugees, by Megan Bradley
02/10/2026 -
International organizations play vital roles in the global governance of refugees, with the Office of the UN High Commissioner for Refugees (UNHCR) spearheading assistance and protection efforts. Yet...
Adaptive respiratory bypass restores oxidative metabolism in NADH dehydrogenase-deficient Escherichia coli
01/10/2026 -
Nicotinamide adenine dinucleotide is central to the cellular redox network and continuously cycles between its oxidized (NAD⁺) and reduced (NADH) forms. Membrane-bound NADH dehydrogenases are the...
Predicting viral host range for reverse zoonosis surveillance
01/10/2026 -
Zoonotic transmission of viruses has triggered major outbreaks throughout history. However, human-to-animal transmission, or reverse zoonotic transmission, also represents an underappreciated public...
Network analysis of correlated conformational dynamics across the evolution of influenza A virus NS1
01/10/2026 -
Protein evolution requires sequence changes to alter molecular properties without disrupting the dynamic organization necessary for function. How residue-level networks of correlated motions...
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