Telecomunicaciones, información y comunicación
De novo design of light-controlled conformational protein switches
28/10/2026 -
Light-responsive proteins offer the ability to control biology at an unmatched resolution. Yet, optogenetics is limited to a relatively small number of natural and engineered photoreceptors. The...
Bayesian in situ point spread function modeling enables high-fidelity three-dimensional nanoscopy in deep tissue
28/10/2026 -
Three-dimensional single-molecule localization microscopy enables nanometer-resolution mapping of biomolecular organization in native cellular environments, but extending this capability to deep...
Transcriptomic profiling of normal and glaucomatous trabecular meshwork cells in a tissue-like soft ECM environment
28/10/2026 -
Purpose. Trabecular meshwork (TM) dysfunction contributes to the elevated intraocular pressure in primary open-angle glaucoma. To better understand the molecular signature distinguishing glaucomatous...
The most important part of AI chatbots is being ignored
28/10/2026 -
AI firms can increase the power of their chatbots without updating to new models. Columnist Jacob Aron explains how a simple bit of software can give AI a boost – and whether AI will soon be able...
Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies
27/10/2026 -
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular...
Programable Acoustic Single‐Cell Manipulation With Model‐Free Machine Learning
27/10/2026 -
Closed‐loop control with ultrasound enables precise, noninvasive manipulation of individual cells inside a microfluidic device using a model‐free reinforcement learning‐inspired algorithm,...
Clarke Transform: A Lingua Franca for Continuum Robotics
27/10/2026 -
Using the Clarke transform, both robot‐dependent mappings are known exactly for kinematic models, leading to a complete chain of transformations between spaces with associated abstraction. This...
The BAF chromatin remodeling subunit ARID1B coordinates cell-cycle exit and motor neuron differentiation
27/10/2026 -
Neuronal differentiation requires precise regulation of transcriptional and epigenetic networks by BAF (BRG1/BRM-associated factor) chromatin remodeling complexes. Mutations in Arid1b, encoding a...
FluxSprout: Single-cell metabolic modeling of vascular sprouting in zebrafish
27/10/2026 -
Genome-scale metabolic modeling offers a powerful framework for identifying cell-state-specific metabolic vulnerabilities, yet its application to heterogeneous biological systems remains limited by...
Extending Musculoskeletal Modelling Validation Beyond Gait: Knee Loading and Kinematics During Daily Activities
27/10/2026 -
Musculoskeletal (MSK) modelling enables non-invasive estimation of internal body loads, which could inform the design of novel orthopedic implants and guide personalized treatment strategies....
Satellites show some of the strongest evidence the AMOC is weakening
26/10/2026 -
The crucial Atlantic current system that brings warmth to Europe has slowed 14 per cent in 30 years, according to an analysis of how much heat the ocean is releasing to the atmosphere
Is GenAI helpful for writing? A re-analysis using robust Bayesian meta-analysis (RoBMA), by Shawn Hemelstrand
26/10/2026 -
A recent meta-analysis showed that genAI has a strong impact on writing. The current analysis instead shows little evidence for this after correcting for publication bias, which is driven mostly by...
Exact many-body wavefunction of the Kondo model with time-dependent interaction strength, by Parameshwar R. Pasnoori, Emil A. Yuzbashyan
26/10/2026 -
Quantum integrability has been applied to a large variety of low dimensional Hamiltonians in Quantum Field Theory, Condensed Matter Physics, and Statistical Mechanics to obtain exact expressions for...
Room-temperature multiferroic semiconductor with electrically switchable valley polarization in Zn-/Cd-intercalated $mathrm{CrSe_2}$, by Jiatian Guo, Hongkuan Yuan, Hong Chen
26/10/2026 -
Purely electrical switching of ferromagnetism-induced valley polarization in two dimensional (2D) ferrovalley materials provides a promising avenue for low-power information processing. Herein, Zn-...
Physics‐Informed Machine Learning for Predicting Phases and Density of Al2O3–TiB2 Composites Synthesized via Laser Ignition From the Al–TiO2–B2O3–H3BO3 Reactive System
26/10/2026 -
This interactive physics‐informed machine learning model predicts the composition and density of advanced ceramic materials produced by self‐propagating high‐temperature synthesis. The model...
Daniel Kahneman's Influence on My Thought
26/10/2026 -
As people think, communicate, and create they often put thought into the world in various forms for themselves and others to expand the mind and to work with the thought. People then see more, or...
Building computational benchmarks: an Omnibenchmark reimplementation of a single-cell preprocessing pipeline evaluation
26/10/2026 -
Background: In the past few years, we have seen a veritable surge in single-cell (e.g., RNA-sequencing) techniques and datasets, enabling increasingly detailed characterization of cellular...
Optimisation of single-nuclei isolation and RNA sequencing of parasitic nematodes
26/10/2026 -
Single-cell/nuclei transcriptomics has revolutionised our understanding of cell, tissue, and organismal biology in humans and model organisms across health and disease. However, for non-model...
Mediterranean diet may boost tiny proteins that protect the heart and brain
24/10/2026 -
Scientists have uncovered a surprising new clue to why the Mediterranean diet is so good for the heart, brain, and healthy aging. Researchers at USC found that older adults who closely followed the...
Scientists discover a hidden switch that burns fat and blocks new fat cells
24/10/2026 -
Scientists have discovered that switching off a protein called Mitch makes human cells burn more fat and prevents new fat cells from developing. The breakthrough builds on experiments in mice that...
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