Telecomunicaciones, información y comunicación

Corpusome, a cross-body-site human microbiome corpus for representation learning
11/09/2026 - Machine-learning models of the human microbiome are trained mostly on stool samples from single cohorts, limiting cross-body-site representation and cross-study generalization. Progress is...
Complementary prefrontal and thalamic representational dynamics during response planning
11/09/2026 - Advance contextual information can guide behavioral responses, but how prospective action representations unfold across prefrontal and thalamic neuronal populations of the cognitive control network...
Atlas-Guided Cell-Specific Transcriptomics Identifies Pathway-Level Remodeling of Human Hypothalamic CRH Neurons in Opioid Use Disorder
11/09/2026 - Opioid use disorder (OUD) disrupts hypothalamic stress signaling, yet the molecular state of human paraventricular nucleus (PVN) corticotropin-releasing hormone (CRH) neurons remains poorly defined....
Data-driven multiscale modeling deciphers MOI-dependent dual antiviral mechanisms of OP7
11/09/2026 - OP7 defective interfering particles are promising antivirals against influenza A virus (IAV), but their antiviral mechanisms are not fully understood. Here, we developed a data-driven multiscale...
Candida albicans promotes self-adhesion and tumor cell progression of colorectal cancer cells.
11/09/2026 - Candida albicans, a benign commensal yeast in the healthy gut, is increasingly being recognized as a tumor-promoting component of the gut mycobiome that is linked to worse patient outcomes in...
Gene repertoire expansion and cis-regulatory diversification shaped 26S proteasome evolution within a proteostasis-centered network
11/09/2026 - The 26S proteasome is essential for proteostasis and constitutes one of the most conserved molecular machineries in eukaryotes. Its homeostasis is maintained by a mechanistically conserved feedback...
Thermodynamic coprocessor for linear operations with input-size-independent calculation time based on open quantum system, by Ivan V. Vovchenko, Alexander A. Zyablovsky, Alexander A. Pukhov, Evgeny S. Andrianov
11/09/2026 - Linear operations, e.g., vector-matrix and vector-vector multiplications, are core operations of modern neural networks. To diminish computational time, these operations are implemented by parallel...
Half-match recombination drives bridge RNA-guided excision and off-target insertion
10/09/2026 - IS110-family bridge recombinases are a recently identified class of compact, RNA-guided editors in which a bridge RNA (bRNA) directs the recombination of a donor DNA into a target site. In the...
Shared Latent Decision Strategies Underlie Reward-Guided Behavior Across Species
10/09/2026 - Adaptive behavior requires that organisms learn which actions are rewarded and to update action selection when the environment changes. While human and non-human animals exhibit adaptive behavior,...
Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms
10/09/2026 - Synaptojanin 1 is a brain enriched phosphoinositide phosphatase implicated in endocytosis at the synapse. A mutation (R258Q) that selectively impairs its Sac1 phosphatase domain causes early onset...
GenomeCompendium: A database for the integrated analysis of repeats, assembly quality and functional content of complete prokaryotic genomes
10/09/2026 - Microorganisms hold great promise for urgent global needs such as increasing sustainable agricultural production while reducing chemical fertilizer and pesticide use or providing novel classes of...
Ozempic and Wegovy linked to nearly 40% fewer asthma attacks
09/09/2026 - Semaglutide, the drug found in Ozempic and Wegovy, was linked to nearly 40% fewer asthma attacks in a large real-world study. It was also associated with about 20% fewer COPD flare-ups. Researchers...
Caffeine may flip an ancient cellular switch linked to slower aging
08/09/2026 - Scientists found that caffeine activates an ancient cellular energy system involved in stress resistance, DNA repair, and growth. The discovery could help explain caffeine’s links to healthier...
Solving the $4 times 4$ quantum Yang-Baxter equation, by Marius de Leeuw, Vera Posch
10/09/2026 - In this paper, we complete the classification of $4×4$ analytic solutions of the Yang–Baxter equation. Regular solutions were recently classified and in this paper we find the remaining...
Full counting statistics in the sine-Gordon model, by Botond C. Nagy, Márton Kormos, Gábor Takács
10/09/2026 - Full counting statistics (FCS) is a dynamical generalisation of the free energy, encapsulating detailed information about the distribution and large-scale correlation functions of conserved charges...
Machine learning we can trust: tensor algebra and the design of reliable foundation models
09/09/2026 - When an AI model answers our question, can we interrogate this particular answer and receive solid reasoning? Twenty‐four centuries ago, Socrates judged understanding not by how fluently someone...
Sampling in structure-token space enables accurate prediction of multiple protein conformations
09/09/2026 - Protein function is fundamentally mediated by ensembles of distinct metastable states. However, existing methods, such as AlphaFold 3, typically exhibit a bias toward predicting a single dominant...
What is it like to be a blob? A distributed, decentred and context-sensitive neurobiology of consciousness
09/09/2026 - Consciousness is often studied by asking whether particular brain regions or systems are privileged. We tested a distributed, decentred and context-sensitive alternative using 579...
The role of cell growth rate on accumulation of the mitotic cyclin Cdc13 in fission yeast
09/09/2026 - Eukaryotic cells control their size by coordinating growth and division. Fission yeast divide at a reproducible cell size due to regulated activation of the cyclin-dependent kinase Cdk1. The nuclear...