Actividades asistenciales

NUCLEOBASE EDITORS AND USES THEREOF
28/08/2025 - Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the...
ANTI-CANCER AGENTS
28/08/2025 - This invention relates to agents, uses and methods for cancer designed to promote anti-tumor effects over a range of different cancers. Exemplary synergistic therapies include compositions of...
CHIMAERIC PROTEINS AND THERAPEUTIC AGENTS
28/08/2025 - Provided is a chimaeric protein comprising a ubiquitin ligase domain and a RAS-specific endogenous targeting portion. The ubiquitin ligase domain may be a VHL E3 ligase domain, or a fragment or...
Compound - diagnostic marker for kidney cancer, method for detecting enzymatic activity, method for diagnosis of kidney cancer, kit comprising the compound, uses of the compound and method for the treatment of kidney cancer
28/08/2025 - The invention relates to a novel chemical compound—a diagnostic marker—for use in medicine, more specifically in cancer diagnosis, in particular the diagnosis of kidney cancer. The invention...
ENGINEERED CRISPR-CAS13F SYSTEM AND USES THEREOF
28/08/2025 - The disclosure provides novel engineered Cas13f effector proteins that substantially maintain guide sequence-specific cleavage activity and substantially lack guide sequence-independent collateral...
TARGETED AUGMENTATION OF NUCLEAR GENE OUTPUT
28/08/2025 - Provided herein are methods and compositions for increasing production of a target protein or functional RNA by a cell.
POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR
28/08/2025 - The present disclosure relates to the technical field of medicines, in particular to a polycyclic poly(ADP-ribose) polymerase (PARP) selective inhibitor compound as shown in general formula (I), a...
METHODS FOR DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE
28/08/2025 - Provided herein are methods for diagnosing and treating Alzheimer's disease in a subject comprising determining the expression level of three, four or five members of a panel of proteins in a...
COMPOUNDS AND METHODS FOR MODULATING SCN2A
28/08/2025 - Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of SCN2A RNA in a cell or subject, and in certain instances reducing the amount of SCN2A...
COMPOSITIONS AND METHODS FOR TREATING TARDBP ASSOCIATED DISEASES
28/08/2025 - The present invention relates to the field of antisense oligonucleotides used to reduce expression of the transactive response DNA binding protein 43 (TARDBP) gene which encodes the protein TAR...
ENGINEERED CRISPR-CAS13F SYSTEM AND USES THEREOF
28/08/2025 - The disclosure provides novel engineered Cas13f effector proteins that substantially maintain guide sequence-specific cleavage activity and substantially lack guide sequence-independent collateral...
COMPOSITIONS AND METHODS FOR USING ENGINEERED DEUBIQUITINASES FOR PROBING UBIQUITIN-DEPENDENT CELLULAR PROCESSES
28/08/2025 - The present disclosure provides, inter alia, a recombinant engineered deubiquitinase (DUB) and methods for treating or ameliorating an inherited ion channelopathy, such as long QT syndrome,...
Cyclic Structured Oligonucleotides as Therapeutic Agents
28/08/2025 - The present invention provides oligonucleotides referred to as cyclic structured oligonucleotides (“CSOs”) comprising a functional domain, a cyclizing domain, and a linker segment as described...
NUCLEOBASE EDITORS AND USES THEREOF
28/08/2025 - Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the...
AUGMENTED REALITY DEVICE FOR PROVIDING AUGMENTED REALITY SERVICE FOR CONTROLLING OBJECT IN REAL SPACE AND OPERATION METHOD THEREOF
28/08/2025 - Provided are an augmented reality device for providing an augmented reality service for controlling an object in a real world space, and an operating method for the same. The method may include...
System and method for auto-generating and sharing customized virtual environments
28/08/2025 - A system for auto-generating and sharing customized virtual environments comprises a processor associated with a server. The processor detects an avatar associated with a user device interacting...
METHOD AND SYSTEM FOR PROVIDING SYNTHETIC EMERGENCY SCENE RECONSTRUCTION
28/08/2025 - Aspects of the subject disclosure may include, for example analyzing emergency communications that were transmitted from end user devices; determining that a group of the emergency communications...
Enhancing Dragline Operational Area Visualization and Positional Analysis for Its Effective Guidance Through Immersive Virtual Reality Inspection
14/05/2025 - A system 100, method 500, autonomous mobile robot 400, and computer readable media enabling location-based autonomous navigation using a virtual world system is provided. The system 100 comprises...
VIRTUAL VISION SYSTEM
28/08/2025 - A context based augmented reality system can be used to display augmented reality elements over a live video feed on a client device. The augmented reality elements can be selected based on a...