Actividades asistenciales

SGC STIMULATORS
13/12/2024
ARTIFICIAL IMMUNE RECEPTORS
12/12/2024 - The present disclosure provides novel polypeptides, so called artificial immune receptors or AlRs, that are novel tools for cellular therapies. AIR-expressing regulatory T cells sense these...
TLR9-TARGETED SPHERICAL NUCLEIC ACIDS HAVING POTENT ANTITUMOR ACTIVITY
12/12/2024 - Aspects of the invention relate to immunostimulatory spherical nucleic acids (IS-SNA) for the treatment of a disorder, such as cancer. The IS-SNA may be administered together with a checkpoint...
FUSION PROTEIN COMPRISING LIGHT PROTEIN AND ANTI-FAP ANTIBODY AND USES THEREOF
12/12/2024 - A fusion protein comprising a LIGHT protein and an antigen-binding site that specifically binds to FAP may exhibit anticancer effects. In particular, the fusion protein efficiently targets cancer...
COMBINATION THERAPY COMPRISING SIRP ALPHA FUSION PROTEIN AND ANTI-CD19 ANTIBODY FOR TREATMENT OF CANCER
12/12/2024 - Combination therapies comprising a SIRPaFc fusion protein and an anti-CD19 agent are provided. The combination therapies can optionally further include an E3 ubiquitin ligase modulator.
AZETIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, PREPARATION METHODS AND THEIR USES IN THE TREATMENT OF CNS DISORDERS
12/12/2024 - The present disclosure relates to compounds of formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, wherein R
STABLE CANNABINOID FORMULATIONS
12/12/2024 - Abstract The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use. -91-