Salud y calidad de vida

SGC STIMULATORS
13/12/2024
ARTIFICIAL IMMUNE RECEPTORS
12/12/2024 - The present disclosure provides novel polypeptides, so called artificial immune receptors or AlRs, that are novel tools for cellular therapies. AIR-expressing regulatory T cells sense these...
TLR9-TARGETED SPHERICAL NUCLEIC ACIDS HAVING POTENT ANTITUMOR ACTIVITY
12/12/2024 - Aspects of the invention relate to immunostimulatory spherical nucleic acids (IS-SNA) for the treatment of a disorder, such as cancer. The IS-SNA may be administered together with a checkpoint...
FUSION PROTEIN COMPRISING LIGHT PROTEIN AND ANTI-FAP ANTIBODY AND USES THEREOF
12/12/2024 - A fusion protein comprising a LIGHT protein and an antigen-binding site that specifically binds to FAP may exhibit anticancer effects. In particular, the fusion protein efficiently targets cancer...
COMBINATION THERAPY COMPRISING SIRP ALPHA FUSION PROTEIN AND ANTI-CD19 ANTIBODY FOR TREATMENT OF CANCER
12/12/2024 - Combination therapies comprising a SIRPaFc fusion protein and an anti-CD19 agent are provided. The combination therapies can optionally further include an E3 ubiquitin ligase modulator.
COMPOSITIONS AND METHODS FOR TREATING MYELIN DISORDERS
12/12/2024 - A method of enhancing oligodendrocyte progenitor cell (OPC) migration, differentiation, proliferation and/or maturation in a subject in need thereof includes administering to the subject a...
NUTRITIONAL COMPOSITION FOR NEURODEGENERATION AND NEUROTRAUMA
12/12/2024 - The invention relates to a nutritional composition comprising a combination of (i) omega-3 fatty acid DHA with (ii) vitamin B2 and (iii) vitamin D3 for use in the treatment of neurodegenerative...
MUSCARINIC RECEPTOR AGONISTS
06/11/2024 - Esta invención se refiere a compuestos y sales de los mismos que son agonistas de receptores muscarínicos, útiles en el tratamiento de enfermedades mediadas por receptores muscarínicos....
Hydrotherapy system
10/12/2024 - A hydrotherapy system can include a tub of tempered water, a cold water tank, and a refrigeration system. The system cools the water in the tub following initial immersion of the patient by using...
AGENT DELIVERY DEVICES
12/12/2024 - A medical device may comprise a flexible sheath defining a lumen extending from a proximal end of the sheath to a distal end of the sheath. The sheath may include a piston slidably received within...
CYCLIC POLYPEPTIDE CARRIER FOR EFFICIENT DELIVERY OF NUCLEIC ACID, AND VARIANTS THEREOF
12/12/2024 - The present invention relates to a novel cyclic peptide carrier in the field of pharmaceutical technology and its various forms, where the cyclic peptide has the general sequence formula...
HYDROGENATED QUINOXALINES
12/12/2024 - Provided is a therapeutic agent for ADHD having an efficacy comparable to that of central nervous system stimulants and the same low risk of drug dependence and abuse as existing non-central...
METHODS FOR UPREGULATING SHANK3 EXPRESSION
12/12/2024 - Aspects of the disclosure relate to non-naturally occurring constructs for the activation of Shank3 gene expression, AAV vectors comprising the constructs, and gene therapy methods.