Medio ambiente y sostenibilidad

Genetic accessibility, not superior fitness, determines which anti-HBs antibody escape variants are selected in patients
08/10/2026 - Background and Aims: Genetic diversity within the hepatitis B virus (HBV) surface antigen (HBsAg) drives the emergence of immune escape variants, but studying this diversity in vivo has been limited...
Approximate local alignment via chained MEM divergence estimation for detecting horizontal gene transfer
08/10/2026 - Local alignment tools struggle at querying against thousands of bacterial genomes, because the reference indexes are memory-intensive and base-level dynamic programming is slow. We present alamem...
SpatialOmicsLab: an integrated research environment for AI co-scientists in spatial transcriptomics
08/10/2026 - Spatial profiling is moving from method development into a central platform for biological discovery and clinical translation, but analyzing such complex data has become the bottleneck of scientific...
Record El Niño threatens Great Barrier Reef with ecological shift
08/10/2026 - Researchers are worried about the impact the strongest-known El Niño will have on the Great Barrier Reef, and whether anything can be done to avert the World Heritage Area’s demise
Scientists accidentally discover a genetic code that breaks the rules of life
08/10/2026 - Scientists accidentally discovered a microscopic organism with a genetic code that breaks a rule researchers thought was nearly universal. While testing a new DNA sequencing technique, they examined...
Exploring the Time–Frequency Quantile Nexus Between SDG 9 and SDG 10 in Latin American Countries
08/10/2026 - This study examines the dynamic nexus between SDG 9 (Industry, Innovation, and Infrastructure) and SDG 10 (Reduced Inequalities) across Latin America using quarterly data and wavelet quantile...
Dynamic Schlafen 11 (SLFN11) expression revealed by single-cell RNA sequencing of clonal human cancer cells
07/10/2026 - Schlafen 11 (SLFN11) is a key determinant of sensitivity to DNA-damaging therapies in multiple cancers including leukemia, Ewing sarcoma, head and neck cancers, mesothelioma and small cell lung...
Multi-modal ion-transport function of potassium channelrhodopsins
07/10/2026 - Light-gated K+ channelrhodopsins (KCRs) are recognized as an ideal neuronal silencing tool in optogenetics. KCRs contain functionally important residues for a light-driven H+ pump bacteriorhodopsin,...
Bacterial Mercury Resistance Reveals a Robust Species-Structured Human Antimicrobial Mobilome
07/10/2026 - Antimicrobial resistance (AMR) is increasingly recognised as an ecological and evolutionary phenomenon that extends beyond clinical environments. Despite the predominant focus on antibiotics,...
Scientists warn a popular vitamin D supplement may have a hidden downside
08/10/2026 - Not all vitamin D supplements are created equal, and new research suggests that one popular form may have an unexpected downside. Scientists found that taking vitamin D2 can actually lower the...
Taking antibiotics? Sugar may be making the damage worse
07/10/2026 - Eating more sugar while taking antibiotics was linked to greater disruption of the gut microbiome and increased growth of potentially harmful bacteria. Researchers say temporarily cutting back on...
Climate Resilience and Environmental Sustainability of Healthcare Facilities in a Rural District of Pakistan: A Mixed‐Methods Assessment Using the WHO Framework
07/10/2026 - A mixed‐methods WHO CRES‐HCF assessment of 12 rural healthcare facilities in Matiari, Pakistan, found only medium climate preparedness (33%–67%), with WASH (41%), workforce (37%), and...
Divergent genotype-phenotype maps determine the capacity for adaptation to antibiotics among Enterobacteria
06/10/2026 - What dictates the extent to which a bacterial strain can evolve under antibiotic pressure remains poorly defined, despite its implications for the effectiveness of antibiotics in clinical practice....
Impaired glycolysis in bone underlies age-related bone loss in mice
06/10/2026 - Bone loss and metabolic dysregulation often coexist in older adults, yet the relationship between age-related changes in bone cell metabolism and bone-forming activity remains unclear. By modeling...
Genetic dissection of grafting traits reveals regulators of graft union formation in grapevine
06/10/2026 - Understanding how grafts form has fascinated scientists for over a century, and numerous transcription regulators involved in wound healing, callus formation, and grafting have been identified in...
Domestication, spread, and improvement have shaped biological nitrogen fixation traits in Zea taxa
06/10/2026 - Synthetic nitrogen fertilizers enhance maize (Zea mays ssp. mays) productivity but impose substantial environmental and economic costs. Some Mexican maize landraces support biological nitrogen...
Convergent and divergent patterns of holobiont evolution in co-distributed chemosynthetic symbioses
06/10/2026 - Intraspecific variation in microbial symbioses is shaped by a variety of ecological and evolutionary processes. In geographically separated populations, divergence in genomic traits is expected due...
Host Cell Wall Polysaccharides Modulate Nanosynbacteria Recognition and Attachment
06/10/2026 - Ultrasmall episymbiotic bacteria grow on the surface of their obligate bacterial hosts. These episymbionts have a restricted host range and likely rely on host-derived receptor molecules to identify...