Ciencias de la vida

The chemoreceptor McpA mediates aerotaxis and redox taxis in Salmonella Typhimurium

30/10/2026 - Redox environments in nature are shaped by reactive oxygen species (ROS), oxygen, and metal ion chemistry, and exert profound effects on bacterial physiology and survival. In some pathogens,...

A Blast Fungus Effector Targets a Tubby-like F-box Protein to Suppress Plant Immunity

30/10/2026 - The blast fungus Magnaporthe oryzae is one of the most destructive pathogens of rice, secreting effector proteins that reprogram host cells to enable infection. Identifying plant targets of these...

Lipid Changes due to Low O-GlcNAc and the Downstream Consequences

30/10/2026 - O-GlcNAc transferase (OGT) is an essential mammalian glycosyltransferase that installs O-GlcNAc onto thousands of cytosolic and nuclear proteins. Dysregulated glycosylation by OGT is associated with...

Differing patterns in community composition and diversity of biofilm-forming bacteria and fungi along a large salinity gradient

30/10/2026 - Aim: Biofilms are complex ecosystems formed by phototrophic and heterotrophic organisms, such as bacteria and fungi. Biofilms are hotspots for microbial activity and crucial for the functioning of...

Identification of TM4SF1 as a novel tumor-associated antigen in biliary tract cancers targetable by CAR-T cell therapy

30/10/2026 - Background & Aims: Biliary tract cancers (BTCs) are a rare set of genetically heterogenous and aggressive malignancies associated with delayed presentation and poor prognosis. Thus, there is an...

Spatial expression evolution of duplicated genes post-whole genome duplication in cultivated tomato

30/10/2026 - The mechanisms by which whole genome duplication contributes to expression divergence of duplicate genes, which can impact the evolution of form and function, has been a long-standing question in...

Single-nucleus transcriptomics links telencephalic cell signatures to ocean acidification effects on social behaviour in a coral reef fish

30/10/2026 - Mutualistic interactions are fundamental to the health and stability of reef ecosystems. While elevated CO2 has been implicated in impairments in interaction behaviours, how this environmental change...

E. coli-produced nanobody fusions as a pan-serotype platform for AAV purification, quantification, and detection

30/10/2026 - Research, production and application of the recombinant adeno-associated virus (rAAV) require versatile tools for rapid and cost-effective advances. We developed fusion constructs with the...

The global geography of threats to freshwater biodiversity

29/10/2026

Genomic erosion across avifauna in a biodiversity hotspot sounds a conservation alarm

29/10/2026

Scientists discover that cranberry juice may help fight tooth decay

29/10/2026 - Cranberry juice may offer an unexpected benefit beyond its reputation for helping prevent urinary tract infections: protecting teeth from decay. Researchers at the University of Illinois Chicago...

Typical entanglement entropy with charge conservation, by Eugenio Bianchi, Pietro Donà, Erick Muiño

29/10/2026 - We consider a many-body Hilbert space with a fixed global charge and show that the typical entanglement entropy of a subsystem, at the leading and subleading order in the thermodynamic limit, can be...

CellMethMarker provides an integrated database of human cell- and tissue-type-specific DNA methylation markers

29/10/2026 - Cell- and tissue-type-specific DNA methylation markers provide epigenetic signatures of cellular identity and are widely used to infer cellular origin from bulk and single-cell methylomes. Existing...

Brain state locks silent memories in a trained fly connectome

29/10/2026 - Complete connectomes now exist for insect nervous systems, but whether a fixed wiring diagram can learn, and what its memories consist of, is unknown. Here, we trained a spiking model of the whole...

The TREM-receptor family interactome in the human brain

29/10/2026 - The Triggering Receptors Expressed on Myeloid cells (TREMs) are a family of cell-surface receptors instrumental in the activation of different myeloid cells. TREM2, its most studied member, is...

A mechanistic classification of GNAO1 mutations links Gβ γ sequestration to hyperkinetic disease and treatment response

29/10/2026 - Gαo is the most prevalent G protein α subunit in the brain and is critical for signal transduction through G protein-coupled receptors. Mutations in the gene encoding Gαo ( GNAO1 ) cause a rare...

NeuroMark-SZ: A Holistic Resting-State-fMRI-Based Model for Divergent Functional Circuitry in Schizophrenia

29/10/2026 - Background: Schizophrenia is a severe neuropsychiatric disorder. Efforts to describe the underlying biology and establish diagnostic markers through non-invasive neuroimaging methods are ongoing,...

Polyaxonal A1 amacrine cells form a spatially extended network in primate retina

29/10/2026 - Inhibitory networks shape information processing in the brain by integrating signals across space, regulating neuronal responses, and controlling the flow of signals through neural circuits....

Spontaneous neural activity in the developing ant olfactory system

29/10/2026 - Spontaneous neural activity is a pillar of mammalian neurodevelopment. In mammals, developing olfactory sensory neurons (OSNs) show spontaneous activity patterns that depend on the olfactory receptor...

Daily briefing: The big push to personalize psychiatry

28/10/2026

De novo design of light-controlled conformational protein switches

28/10/2026 - Light-responsive proteins offer the ability to control biology at an unmatched resolution. Yet, optogenetics is limited to a relatively small number of natural and engineered photoreceptors. The...