Ciencias de la vida

ASPIRATION CATHETER SYSTEMS
11/06/2026 - Methods and apparatuses for blood clot aspiration. Described are fluid management components and assemblies for blood clot extraction from a patient's body and for filtering blood and...
A STENT AND STENT DELIVERY SYSTEM
28/05/2026 - The invention relates to modification in stent, with a segment of scarce struts to allow unimpeded blood flow in side branch and also relates to stent delivery system comprising a shaft with over...
SYSTEMS, DEVICES, AND METHODS FOR TREATING VESSEL OCCLUSIONS
21/05/2026 - Treatment devices and associated methods and systems are disclosed herein. According to some embodiments, the present technology includes a treatment device including a tubular member having a...
SUPPORTS FOR ANTENNAS OF BODILY IMPLANTS
11/06/2026 - A device (100) includes a bodily implant (101) having a housing (110) defining a cavity. The housing has a top portion. The device includes an electronic control system (108) that is at least...
BIOINDUCTIVE ANCHOR AUGMENT FOR TISSUE REPAIR
11/06/2026 - A suture anchor augment includes middle and anchor portions configured to insert within an opening formed in bone of a patient, where it is wrapped around an anchor fixation device. The augment...
PTPN2/PTP1B DEGRADERS AND THERAPEUTIC METHOD THEREOF
11/06/2026 - The present disclosure generally relates to compounds (I) that bind to PTPN2/PTP1B and act as degraders of PTPN2/PTP1B, wherein each group is as defined in this disclosure.
METHODS OF TREATING IMPAIRED GLUCOCORTICOID SIGNALLING IN UTERINE DISORDERS
11/06/2026 - [0000] The present disclosure relates to methods of modulating FK506-binding protein-51 (FKBP51) mediated glucocorticoid signalling and HSD11B1 expression in uterine disorders. Further...
BIFUNCTIONAL BET BINDING COMPOUNDS AND USES THEREOF
11/06/2026 - Provided herein are heterobifunctional compounds that bind a targeting moiety (e.g., a transcription factor) and a BET protein. The compounds selectively inhibit proliferation and induce apoptosis...
QUINOLIZINONES AS PI3K INHIBITORS
11/06/2026 - Novel PI3K inhibitors of the general Formula (1) are described along with methods of their preparation and their use in the treatment of diseases associated with the elevation or activation of the...
LINKER FOR ANTIBODY-DRUG CONJUGATES AND ANTIBODY-DRUG CONJUGATES COMPRISING THE LINKER
11/06/2026 - Disclosed herein are linkers suitable for use in antibody-drug conjugates (ADCs), and ADCs comprising the linkers. The ADCs may be suitable for treating or preventing cancer, such as head and neck...
BISPECIFIC LYMPHOTOXIN B RECEPTOR BINDING PROTEINS
11/06/2026 - The present disclosure is directed to bispecific binding proteins and their utility for treating cancer. The disclosed bispecific binding proteins comprises a LTβR binding domain that binds to...
COMPOSITIONS AND METHODS FOR TREATMENT OF CANCERS
11/06/2026 - [0000] The present disclosure provides methods for treating cancer or for increasing a sensitivity of a plurality of cancer cells to a chemotherapeutic agent.
BUFADIENOLIDE COMPOUNDS SUBSTITUTED BY A NITROGEN HETEROCYCLE
11/06/2026 - The invention relates inter alia to compounds of formula (I) and their use in treating or preventing cancer, including metastasis of cancer.
NLRP3 INHIBITOR FOR USE IN TREATING MYELOID DISEASES
11/06/2026 - The present disclosure relates to the field of pharmacy, particularly to a NLRP3 inhibitor, for use in treating myeloid diseases, in particular myelodysplastic syndrome (MDS), chronic...
MITOTIC CELL PHASE ENRICHMENT AND IONIZING RADIATION
11/06/2026 - The invention relates to a combination therapy comprising administering a mitotic-phase (M-phase) cell cycle arresting compound and a modulator of an interphase cell cycle checkpoint to a subject...
TREATMENT FOR CNS-RELATED DISEASE
11/06/2026 - The present invention relates to the field of therapy and drug delivery. More in particular, the invention relates to a therapeutic combination comprising a saponin component and an...
METHOD AND SYSTEM FOR MONITORING BIOLOGICAL PRODUCTS AND METHOD FOR PREDICTING MICROBIAL LOAD IN BIOLOGICAL PRODUCTS
28/05/2026 - The present invention relates to a method and system for monitoring biological products, and also to a method for generating a prediction of microbial load in biological products, comprising at...
METHOD FOR DELAYING OR REDUCING PIGMENTATION DEFECTS OF THE SKIN USING A DATE PALM EXTRACT
11/06/2026 - The invention relates to a method of cosmetic treatment for delaying or reducing skin pigmentation defects and increasing the expression of sirtuin-1, 2, 3 and 6, comprising the step of applying...
ENGINEERED EXOSOMES FOR TREATMENT OF METABOLIC DISORDERS
28/05/2026 - Disclosed is an engineered exosome, comprising (a) an FGF21 polypeptide, fused to a first anchoring polypeptide, (b) an IL-27 polypeptide, fused to a second anchoring polypeptide, and (c) an...