Ciencias de la vida

COMBINATIONS COMPRISING ROGINOLISIB
10/09/2026 - Roginolisib, or a pharmaceutically acceptable salt thereof, for use in the treatment of a haematological malignancy in a subject, wherein said treatment comprises the separate, sequential or...
Method of Treating Cancer
10/09/2026 - A method to enhance immune checkpoint blockade in breast cancer and other solid tumors and hematologic tumors by administering a PD-1/PD-L1 inhibitor together with branched-chain amino acids...
Anti-human integrin alpha3/Beta1 antibodies and methods of use therefor
10/09/2026 - [0000] Disclosed is a monoclonal antibody, MAb51-31 mAb, and its fragments and derivatives that recognize a conformational epitope of human integrin α3/β1 (ITGα3/β1) complex, which is...
AGENTS FOR THE TREATMENT OF PRE-CACHEXIA
10/09/2026 - The present invention relates to the treatment of pre-cachexia using agents that are capable of inhibiting the interaction between hGDF-15 and hGFRAL. The present invention also relates to the...
ENGINEERED IGA ANTI-EPITHELIAL CELL ADHESION MOLECULE
10/09/2026 - Provided herein are engineered IgA antibodies that comprises: (a) an EPCAM binding domain and (b) an IgA heavy chain constant region. Also, provided herein are methods of treating cancer in a...
BIOMARKERS FOR LUNG ADENOCARCINOMA (LUAD), AND METHOD FOR TREATING LUAD
10/09/2026 - [0000] The present invention provides a method for predicting clinical outcomes of a lung cancer patient, such as LUAD, particularly LUAD with low expression of NKX2-1. Also provided includes a...
DELIVERY OF PROTEIN EXTRACELLULARLY
10/09/2026 - The described technology pertains to biotechnology, specifically engineered bacterial systems designed for extracellular delivery of therapeutic proteins in cancer treatment. The disclosed...
METHODS OF TREATING FAMILIAL ADENOMATOUS POLYPOSIS
10/09/2026 - Disclosed herein are methods of treating familial adenomatous polyposis (FAP) in a patient comprising orally administering...
USE OF BAIAP2 INHIBITORS SUCH AS SUBSTITUTED PHENAZINES TO TREAT CANCER
10/09/2026 - Disclosed are small molecule inhibitors useful in reducing or ameliorating the proliferation and migration of cancer. Pharmaceutical compositions containing the small molecule inhibitors are also...
HETEROCYCLIC COMPOUNDS THAT INHIBIT TYROSINE KINASE 2 (TYK2) ACTIVITY
10/09/2026 - The present disclosure relates to heterocyclic compounds suitable for inhibiting or regulating the activity of tyrosine kinase 2 (TYK2). Specifically, the present disclosure relates to compounds...
LACTAM DERIVED COMPOUNDS AS INHIBITORS OF THE STAT6 PATHWAY
10/09/2026 - Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically˗acceptable salts thereof, and wherein R1 is (II) are useful as STAT6 pathway modulators. All the...
TREATMENT OF CANCER USING ARIPIPRAZOLE AND ANTICANCER AGENT
10/09/2026 - [0000] The present disclosure provides a method of treating a cancer in a subject in need thereof, the method comprising: administering aripiprazole and an anticancer agent.
TARGETING OF SIALYL TN-EXPRESSING SOLID TUMORS
10/09/2026 - The present disclosure provides two STn targeting units derived from two antibodies AM51.1 and AM52.1. Immunoreactivity of AM51.1 and AM52.1 was only detected in epithelial tumor tissues, while no...
COMBINATION THERAPIES FOR TREATING CANCER
10/09/2026 - Provided are methods of treating cancer that comprise administering a polypeptide (e.g. a fusion polypeptide) that comprises a SIRPα D1 domain variant and an Fc domain variant in combination with...
USE OF BAIAP2 INHIBITORS SUCH AS SUBSTITUTED PHENAZINES TO TREAT CANCER
10/09/2026 - Disclosed are small molecule inhibitors useful in reducing or ameliorating the proliferation and migration of cancer. Pharmaceutical compositions containing the small molecule inhibitors are also...
VIDEO MODEL FOR MEDICAL 3D SEGMENTATION
10/09/2026 - [0000] A method for using a video model for medical three-dimensional (3D) segmentation includes dividing 3D medical image data into one or more two-dimensional (2D) images. The method includes...
METHODS AND APPARATUS FOR RADIOTHERAPY MOTION MANAGEMENT
10/09/2026 - A method (300) is disclosed for radiotherapy motion management. The method comprises receiving a sequence of 2D images of a patient (310), each image representing patient anatomy at a time...
TECHNOLOGY-DRIVEN MEDICATION MANAGEMENT SYSTEM FOR THE SECURE PERSONALIZED ASSOCIATION OF MEDICINES TO PATIENTS
27/08/2026 - [0000] A technology-driven medication management system and method for the secure dispensing of prescription and other medicines to patients, which in particular tailored to the patient's...
SYSTEMS AND METHODS FOR COMBINED CO2 STORAGE AND METAL EXTRACTION FROM ULTRAMAFIC ROCK AND MINE TAILINGS
10/09/2026 - Nickel and cobalt-containing silicate feedstocks, e.g., ultramafic rock and mining tailings, are reacted with CO2-rich aqueous solutions at fluid:solid ratios below 10, and in the presence of...
NANOPARTICLE FOR TREATING ACNE
10/09/2026 - The invention provides compositions comprising recombinant targeting peptides that bind specifically to the cell wall of Cutibacterium acnes. The compositions find use in controlling, improving...
TABLEWARE WITH SELF-ADHESIVE LIQUID SILICONE RUBBER STRUCTURE
10/09/2026 - [0000] Provided is a tableware with a self-adhesive liquid silicone rubber structure, which includes a tableware base and a self-adhesive liquid silicone rubber layer. The tableware base has a...