Ciencias de la vida
Response to the letter of Deng et al
17/03/2026 -
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NON-SYSTEMIC MRNA ADMINISTRATION
20/03/2026 -
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Insecticidal activity of a Pseudomonas sp. isolated from cabbage root fly (Delia radicum L.) larvae exposed to D. radicum-suppressive soil
13/01/2021 -
Se divulgan composiciones que comprenden compuestos de la Fórmula <strong>I</strong> y compuestos de la Fórmula <strong>II.</strong>...
STABLE CONCENTRATED RADIONUCLIDE COMPLEX SOLUTIONS
06/03/2026 -
본 발명은 진단 및/또는 치료 목적을 위한 약물 제품으로서의 용도를 가능하게 하는, 고농도 및 높은 화학적 안정성의 방사성핵종 복합체 용액에...
-ICOS ANTI-ICOS ANTIBODIES
06/03/2026 -
ICOS (유도성 T 세포 보조자극제)와 결합하는 항체. 조절 T 세포와 효과기 T 세포 간의 비율을 조절하여 환자의 면역계를 자극하기 위한, 암을...
[8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl] (1H-1,2,3-triazol-4-yl)methanones
07/05/2018 -
The present invention covers [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanone compounds of general formula (I): , in which R1, R2, R3, R4 and R5 are as defined...
PEGYLATED CARFILZOMIB COMPOUNDS
24/11/2017 -
The present invention provides polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula I Formula I wherein R1, R2, linker, PEG, n and o are as defined...
MACROCYCLIC INDOLE DERIVATIVES
19/11/2017 -
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EP4 PHARMACEUTICAL COMBINATION OF AN EP4 ANTAGONIST AND IMMUNE CHECKPOINT INHIBITORS FOR THE TREATMENT OF TUMOURS
06/03/2026 -
본 발명은 화학식 (R)-4-(1-(6-(4-(트리플루오로메틸)벤질)-6-아자스피로[2.5]옥탄-5-카복사미도)사이클로프로필)-벤조산의 EP4 길항제 또는 이의...
Novel substituted benzimidazoles, processes for their preparation, pharmaceutical preparations comprising them and their use for preparing medicaments
30/11/2017 -
The present application relates to novel substituted benzimidazoles, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases,...
암의 치료에 유용한 TFGβ 길항제 전구약물을 함유하는 제제화된 및/또는 공동-제제화된 리포솜 조성물 및 그의 방법
12/03/2026 -
TB 전구약물을 포함하는 제제화된 및/또는 공동-제제화된 리포솜, 지질 나노입자 (LNP) 및 고체-지질 나노입자 (SLNP), 및 LNP 및 SLNP의 제조 방법이...
CYCLIC DINUCLEOTIDES AS STING AGONISTS
17/01/2020 -
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as...
GPCR GPCR HETEROMER INHIBITORS AND USES THEREOF
12/03/2026 -
본 발명은 암과 연합된, CXC 수용체 4 (CXCR4)의 억제제-G 단백질-연결된 수용체 (GPCR) 헤테로머들 (CX-CR4-GPCR 헤테로머들)에 관계하며, 여기에서 CXCR4는...
METHODS AND ASSAYS FOR MODULATING GENE TRANSCRIPTION BY MODULATING CONDENSATES
05/03/2026 -
응축물 형성, 구성, 유지, 용해 및 규제를 조정함으로써, 유전자 규제를 조정하는 조성물들과 방법들이 본원에서 기술된다.
Radio-Pharmaceutical Complexes
10/12/2017 -
The invention provides a method for the formation of a tissue-targeting thorium complex, said method comprising; a) forming an octadentate chelator comprising four hydroxypyridinone (HOPO)...
Wnt inhibitors in the treatment of fibrosis
22/12/2017 -
The present disclosure relates to a Wingless-type (wnt) inhibitor of formula (I) for use in the treatment of fibrosis and some fibrosis mediated disorders such as stiff skin syndrome and systemic...
用于调节ERK活性的化合物和组合物
24/03/2026 -
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作为CSF1R抑制剂的5-氰基-1H-咪唑-2-甲酰胺化合物
24/03/2026 -
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