Ciencias de la vida

AMINO-ALCOHOL COMPOUNDS AND THEIR USE IN THERAPY
17/06/2026 - The invention relates inter alia to compounds of formula (I) and their use in treating or preventing cancer, including metastasis of cancer.
COMBINATION THERAPY FOR THE TREATMENT OF METASTATIC CANCER
17/06/2026 - The present invention relates to a combination of (i) an anti-Fibroblast Activating Protein α (FAP) antibody-cytolysin conjugate having the formula A-(L-D)<sub>p</sub> or a pharmaceutically...
ANTIGEN-BINDING POLYPEPTIDES AGAINST CD203A
17/06/2026 - The invention relates to antigen-binding polypeptides comprising the CDR1, CDR2 and CDR3 region of a VHH domain of a camelid heavy chain antibody. The polypeptides bind specifically to CD203a and...
NEW FUSION PROTEIN AGAINST ANGIOGENESIS
17/06/2026 - The present invention provides a new bi-functional fusion protein TC1545, simultaneously targeting vascular endothelial growth factor (VEGF) and angiopoietins (ANGs) with a higher monomer purity....
KYNURENINE PATHWAY ENZYME INHIBITORS FOR USE IN THE TREATMENT OF MYCOSES CAUSED BY TRICOPHYTON RUBRUM
17/06/2026 - The object of the invention is an inhibitor of the kynurenine pathway enzyme selected from a group comprising 1-methyltryptophan, aminooxyacetic acid, 2-aminoadipic acid,...
TRYPTOPHAN OR ITS METABOLITE FROM THE KYNURENINE PATHWAY FOR USE IN THE PREVENTION OR TREATMENT OF DERMATOPHYTOSIS
17/06/2026 - The object of the invention is tryptophan or metabolite thereof from the kynurenine pathway selected from a group comprising 3-hydroxykynurenin, quinolinic acid, kynurenic acid, quinaldic acid and...
METHODS AND SYSTEM FOR TRAINING AND USING A NEURAL NETWORK FOR DETERMINING A DOSE DISTRIBUTION IN RADIOTHERAPY
17/06/2026 - The present disclosure relates to a method for training and using a neural network for determining a dose distribution in a patient in radiotherapy. The disclosure further relates to a method and...
POLYPEPTIDES AND COMPOSITIONS FOR ORAL ADMINISTRATION AND METHODS OF USE THEREOF
28/05/2026 - Disclosed herein are compositions and constructs related to a polypeptide, PT-X'n-PTA-Hm (1 ), or pharmaceutically acceptable salts thereof, wherein PT is a peptide transport or fragment thereof;...
NOVEL USE OF PYNEGABINE IN PREPARATION OF DRUGS AGAINST PSYCHIATRIC DISORDERS
22/05/2026 - Provided in the present invention is a novel use of Pynegabine as represented by formula (I) in the preparation of drugs for treating or preventing psychiatric disorders such as depression and...
MICROSTRUCTURE AND METHOD FOR MANUFACTURING SAME
28/05/2026 - A microstructure is disclosed. The microstructure according to one aspect of the present invention comprises: a core part; and a plurality of edge parts radially disposed around the core part,...
LOCALIZATION TAG DEPLOYMENT SYSTEM AND METHOD
28/05/2026 - A deployment system for accurate placement of localization tags within biological tissue is disclosed. The system comprises a catheter hub with sheath, a stylet, and a loader. The catheter hub...
METHODS FOR FREEZE-DRYING BACTERIA AND UTILITY AS A MUCOSAL VACCINE PLATFORM
28/05/2026 - Embodiments of the present disclosure generally relate to compositions of a lyophilized (freeze dried) Listeria strain based therapeutics and a method for lyophilizing compositions of the...
APPARATUS AND METHOD FOR DETERMINING RISSER GRADE
28/05/2026 - The present invention relates to an apparatus and method for determining a Risser grade, and according to an embodiment of the present invention, the apparatus comprises: an image extraction unit...
CTP-BASED VOF DETECTION METHOD AND SYSTEM
28/05/2026 - The present invention relates to a computed tomography perfusion (CTP)-based venous output function (VOF) detection method and system, and the CTP-based VOF detection method performed by the...
SUPERVISED ARTIFACT REDUCTION IN X-RAY IMAGES
28/05/2026 - The presently disclosed subject matter addresses the intrinsic limitation that artifact- free ground-truth X-ray images cannot be physically acquired, restricting the use of direct supervised...
METHOD AND APPARATUS FOR PREDICTING OSTEOPOROSIS ON BASIS OF X-RAY IMAGE
28/05/2026 - A method and an apparatus for predicting osteoporosis on the basis of an X-ray image are disclosed. The disclosed apparatus comprises: an image segmentation module, which receives an X-ray image...
APPARATUS AND METHOD FOR ESTIMATING SEVERITY OF PULMONARY CONTUSION ON BASIS OF ARTIFICIAL INTELLIGENCE
28/05/2026 - An apparatus and a method for estimating the severity of pulmonary contusion on the basis of artificial intelligence are disclosed. The method for estimating the severity of pulmonary contusion on...
APPARATUS AND METHOD FOR AUTOMATICALLY SEGMENTING BRAIN TISSUE FROM COMPUTED TOMOGRAPHY IMAGE ON BASIS OF ARTIFICIAL INTELLIGENCE
28/05/2026 - The present invention relates to a brain tissue segmentation apparatus and method for precisely segmenting brain tissue on the basis of a CT image to distinguish gray matter (GM), white matter...
VOLUMETRIC NEUROPATHOLOGY ASSESSMENT
28/05/2026 - The invention relates to systems, methods, and computer-readable media for automated assessment of volumetric changes in brain regions of interest in preclinical animal models. Digital images of...
SYSTEMS AND METHODS FOR HEALTHCARE CONFIGURED ARTIFICIAL INTELLIGENCE PLATFORMS
28/05/2026 - A device may include a plurality of sensors configured to collect operational data from a healthcare environment, the operational data comprising at least two of patient data, equipment status...
ANTIMICROBIAL COMPOSITION WITH COLLOIDAL SILVER NANOPARTICLES, PRODUCTION METHOD AND USES OF SAME
28/05/2026 - The present invention relates to a bioactive scaffold comprising a silver-loaded antimicrobial composition, which acts as a therapeutic device, especially a scaffold, for wound healing and other...