Ciencias de la vida
SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE
20/11/2025 -
The invention relates to furopyridine compounds of formula (I) for use in the treatment of FLT3-related, DDR-related and MAP4K-related diseases.
Inhibition of DRP1-mediated Mitochondrial Fission and NRF2/HO-1/GPX4-mediated Ferroptosis by Mdivi-1 Protects Against Vascular Cognitive Impairment
08/07/2025 -
The present invention provides polynucleotide vectors for high expression of heterologous genes, and methods for constructing such vectors. Some vectors further comprise novel transposons and...
FORMULATIONS OF PECTOLINARIGENIN
20/11/2025 -
The invention provides compositions comprising pectolinarigenin. The compositions of the invention may be administered topically, on the skin of the subject. The invention further provides methods...
ENVIRONMENT CONTROLLING ENCLOSURE
20/11/2025 -
There is provided a plant environmental enclosure (14) for a plant container (2) with a permeable sidewall (6), the plant environmental enclosure (14) comprising a cover configured to, in use,...
NECTIN-4 BINDING AGENTS
30/11/2023 -
The invention relates to antibodies and antibody fragment that bind to Nectin-4 polypeptides. The invention also relates to antibody-drug conjugates that comprise the antibodies or antibody...
SOTORASIB FOR USE IN THE TREATMENT OF CANCER
18/11/2025
CAMPTOTHECIN DERIVATIVES THAT BIND TO DDX5 PROTEIN AND PRODRUGS THEREOF
10/07/2025 -
The present invention relates to (a) an active camptothecin derivative represented by Chemical Formula 1 below, which is designed to bind to the DDX5 protein and an E3 ligase; (b) a prodrug...
INHIBIDORES DE PROTEÍNAS DE FUSIÓN DE KLK5
15/02/2024 -
Se describen polipéptidos que son útiles para, entre otras cosas, inhibir o suprimir la actividad de una proteasa relacionada con calicreína y, por lo tanto, tratar enfermedades y afecciones...
INHIBIDORES DE MIELOPEROXIDASA
15/02/2024 -
La memoria descriptiva se refiere en general a compuestos de Fórmula (I), (Ia), y (Ib): (I) (Ia) (Ib) y sales farmacéuticamente aceptables de los mismos, donde X, Y1, Y2, Y3, Y4, y Y5 y X1, X2,...
INHIBIDORES DE INFLAMASOMA NLRP3
15/02/2024 -
La presente invención se refiere a nuevos compuestos de piridazin-3-ilo fenol de fórmula (I), en donde R1, R2, R3, R4 y R5 se definen en el presente documento, que inhiben la actividad del...
FULL-SIZE SEPARATION AND PRE-ENRICHMENT SYSTEM AND PROCESS FOR COAL-ASSOCIATED GALLIUM AND LITHIUM-BEARING MINERALS
22/01/2025 -
The present disclosure relates to a full-size separation and pre-enrichment system and process for coal-associated gallium and lithium-bearing minerals, and belongs to the technical field of...
In situ and ex situ conservation of Cereus fernambucensis Lem. (Cactaceae) seeds
22/10/2025 -
본 발명은 탄소 격리 극대화, 생산성 향상, 지속 가능한 농업 및 온실 가스 배출 최소화를 위한 농업 관행에 관한 것이다. 본 발명의 방법은 일...
Compuestos derivados benzimidazólicos farmacológicamente activos, con alta afinidad a los receptores MT1 y MT2 de la melatonina y baja afinidad a las enzimas del complejo CYP450, especialmente a la CYP1A2. Sus composiciones farmacéuticas aceptables y procedimiento de producción de los mismos.
29/02/2024 -
La presente invención se refiere a compuestos derivados del benzimidazol, novedosos e innovadores, con actividad farmacológica, los cuales sorprendentemente presentan una alta afinidad por los...
INHIBIDORES DE MIELOPEROXIDASA
15/02/2024 -
La memoria descriptiva se refiere en general a compuestos de Fórmula (I), (Ia), y (Ib): (I) (Ia) (Ib) y sales farmacéuticamente aceptables de los mismos, donde X, Y1, Y2, Y3, Y4, y Y5 y X1, X2,...
In silico method for calculating perfusion metrics, which involves calculating the arterial input function based on a parallel or serial distribution model
17/11/2025 -
Zgłoszenie dotyczy sposobu wyliczania in silico tętniczej funkcji wejściowej (AIF), przy czym sposób obejmuje wybieranie klasy (CM, CMC) i rzędu (n) modelu farmakokinetyki. Klasa modelu...
Introduction to enzymes
14/11/2025 -
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A VVN001-CONTAINING OPHTHALMIC COMPOSITION
08/07/2025
ENHANCED POLYNUCLEOTIDE CONSTRUCTS FOR EUKARYOTIC GENE EXPRESSION
08/07/2025 -
The present invention provides polynucleotide vectors for high expression of heterologous genes, and methods for constructing such vectors. Some vectors further comprise novel transposons and...
Actividades asistenciales
Agroalimentación
Automoción y nueva movilidad
Energía sostenible y eficiente
Materiales avanzados
Medio ambiente y sostenibilidad
Patrimonio natural y cultural
Procesos productivos e industria 4.0
Química y biotecnología
Salud y calidad de vida
Transformación digital



