Ciencias de la vida

COMBINATION THERAPY COMPRISING A MULTI-SPECIFIC BINDING AGENT TARGETING PD-1/PD-L1 AND VEGF/VEGFR AND A MULTI-SPECIFIC BINDING AGENT TARGETING EPCAM AND 4-1BB FOR CANCER TREATMENT

17/09/2026 - The present disclosure relates to combination therapy using a binding agent that binds to (i) PD-1, PD-L1, or both, and (ii) VEGF, VEGF receptor (VEGFR), or both in combination with a binding...

SOLID DISPERSIONS OF ELACRIDAR

17/09/2026 - The present invention relates to a solid dispersion comprising: elacridar or a pharmaceutically acceptable salt thereof, and one or more carrier materials; wherein the one or more carrier...

CRYSTAL FORM OF A PARP1 INHIBITOR SALT AND PREPARATION THEREOF

17/09/2026 - A crystal form (Type A) of the bis-tartrate ((2R,3R)) salt of 7-((4-(2-fluoro-6- (methylcarbamoyl)pyridin-3-yl)piperazin-1-yl)methyl)-3,6-difluoropyrazolo[1,5- a]quinoxalin-4(5H)-one (Formula...

ALGINATE-BASED HYDROGEL COMPOSITIONS AND USES THEREOF

17/09/2026 - The present invention relates to hydrogel compositions comprising oxidized and chemically modified alginate. Such hydrogel is suitable for encapsulating active ingredients, such as T cells, with...

VISMODEGIB FORMULATION

17/09/2026 - Presented invention relates to a pharmaceutical composition comprising polymorphic Form B of Vismodegib having particle size distribution D(90) between 150 µm and 190 µm, preferably between 160...

PDL1-TARGETED IL-12 FUSION PROTEINS

17/09/2026 - This disclosure relates, inter alia, to compositions comprising and methods making and using fusion proteins comprising a PDL1 binding domain and a human IL-12 domain, including immune cells...

SUBSTITUTED 1 H,4H,5H-PYRROLO[3,2-B]PYRIDIN-5-ONE COMPOUNDS AS TEAD BINDERS AND/OR INHIBITORS OF YAP-TEAD AND TAZ-TEAD PROTEIN-PROTEIN INTERACTION

17/09/2026 - The present invention relates to bicyclic compounds. These bicyclic compounds are useful as TEAD binders and/or inhibitors of YAP-TEAD and TAZ-TEAD protein-protein interaction or binding and for...

T CELL RECEPTORS (TCRS) TARGETING ACTIN-LIKE PROTEIN 8 (ACTL8) FOR USE IN THERAPY

17/09/2026 - The present invention provides, amongst others, a T cell receptor (TCR) that binds to an epitope of human Actin-like protein 8 (ACTL8), wherein said epitope consists of the amino acid sequence of...

DHX8/16 INHIBITORS

17/09/2026 - The invention relates to compounds of the general formula I, and the use of the compounds of the present invention for the treatment and/or prevention of diseases and disorders in mammals,...

1-(5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-1H-PYRROL-3-YL)-N-METHYLMETHANAMINE-ION EXCHANGE RESIN COMPLEX, ORALLY DISINTEGRATING TABLET COMPRISING SAME, AND METHOD FOR PREPARING SAME

03/09/2026 - The present invention relates to a 1-(5-(2,4-difluorophenyl)-1-((3-fluorophenyl)sulfonyl)-4-methoxy-1H-pyrrol-3-yl)-N-methylmethanamine-ion exchange resin complex having excellent dissolution...

BLOOD-BASED COMPOSITIONS

03/09/2026 - Provided herein are blood-based compositions. Some such compositions include processed platelet rich plasma (PRP). The composition may include growth factors, a mucoadhesive or thickening agent,...

ORALLY DISINTEGRATING TABLET COMPRISING 1-(5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-1H-PYRROL-3-YL)-N-METHYLMETHANAMINE, AND METHOD FOR PREPARING SAME

03/09/2026 - The present invention relates to an orally disintegrating tablet comprising 1-(5-(2,4-difluorophenyl)-1-((3-fluorophenyl)sulfonyl)-4-methoxy-1H-pyrrol-3-yl)-N-methylmethanamine, the tablet having...

ANTI-KIT ANTIBODY DOSING AND METHODS

03/09/2026 - Provided herein are methods for using antibodies that immunospecifically bind to KIT, a receptor tyrosine kinase, in particular barzolvolimab, to treat, manage or prevent prurigo. Also provided...

COMPOSITIONS AND METHODS FOR TREATING OPHTHALMIC CONDITIONS

03/09/2026 - The described technology pertains to biotechnology, specifically liposomal formulations and methods for targeted delivery of rho-kinase inhibitors to address ophthalmic conditions.

TOPICAL ANESTHETIZING DEVICE

03/09/2026 - Embodiments of the present invention relate to a topical anesthetizing device (TAD) and method for topically anesthetizing an epithelial surface of a mammal are provided. The TAD may include a...

An equipment for the collection of biological material

08/09/2026

医学影像处理方法、系统、设备及介质

22/09/2026 - ...

Ecological vegetation regreening device suitable for building ridges and retaining water for tailings ponds

07/07/2026 - The invention discloses a bank building and water retention ecological vegetation regreening device suitable for a tailing pond, and belongs to the technical field of tailing pond ecological...

Plant planting method based on low tidal flat region

03/07/2026 - The invention discloses a plant planting method based on a low tidal flat region. The method comprises the steps that a planting area is arranged, one or more rows of timber piles are arranged on...

IMAGING DEVICE FOR ENDOSCOPE, AND ENDOSCOPE SYSTEM

03/09/2026 - This imaging device for an endoscope comprises: one or more imaging units; a serializer for converting a plurality of video signals captured by the one or more imaging units into one signal; and a...

MEDICAL LIGHT SOURCE DEVICE

03/09/2026 - This medical light source device comprises: a light source that outputs light for providing white light for illumination and excitation light for medication excitation; and an optical system that...